Volpe J J
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
Clin Perinatol. 1989 Jun;16(2):361-86.
Intraventricular hemorrhage of the premature infant originates in the subependymal germinal matrix. Important neuropathological complications of the hemorrhage are post-hemorrhagic hydrocephalus and periventricular hemorrhagic infarction. The latter infarction and the ischemic lesion, periventricular leukomalacia, are the most important forms of brain injury in the premature infant. Pathogenesis of intraventricular hemorrhage relates to intravascular, vascular, and extravascular factors.
早产儿脑室内出血起源于室管膜下生发基质。出血的重要神经病理学并发症是出血后脑积水和脑室周围出血性梗死。后者的梗死以及缺血性病变——脑室周围白质软化，是早产儿脑损伤的最重要形式。脑室内出血的发病机制与血管内、血管和血管外因素有关。
