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疑似结核病患者胸部X线和胸部计算机断层扫描的评估

Evaluation of Chest X-ray and Thoracic Computed Tomography in Patients with Suspected Tuberculosis.

作者信息

Durmus Mehmet Sait, Yildiz Ismail, Sutcu Murat, Bulut Muhammet, Varkal Muhammet Ali, Ertem Furkan Ubeydullah, Kilic Ayse, Oguz Fatma, Unuvar Emin, Yekeler Ensar

机构信息

Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Merkez mah. Silahtaraga cad, No:73 Eyüp, Istanbul, Turkey.

出版信息

Indian J Pediatr. 2016 May;83(5):397-400. doi: 10.1007/s12098-015-1949-2. Epub 2015 Dec 3.

DOI:10.1007/s12098-015-1949-2
PMID:26634258
Abstract

OBJECTIVE

To investigate if there is any correlation between positive findings detected by posterior-anterior (PA) chest radiograph and thoracic computerized tomography (CT) in cases with suspected lung tuberculosis (TB) due to positive tuberculin skin test (TST) results.

METHODS

This is a retrospective evaluation of the medical files of patients who visited the Department of Pediatrics, Istanbul University, Istanbul Faculty of Medicine from 2006, through 2011 as outpatients and had positive TST (>15 mm) results.

RESULTS

A total of 326 patients were included in the study; 45.7 % (n = 149) were girls, and the mean age was 9.0 ± 4.1 y (range: 1-17 y). In total, 14.4 % (n = 47) had TB findings, all of which were in the form of hilar lymphadenopathy. Among the 47 cases with TB findings in PA chest X-ray, 45 (95.7 %) also had findings in thoracic CT. Only 2 (4.3 %) patients had normal thoracic CT results although their PA chest X-ray results were positive.

CONCLUSIONS

Evaluation for pulmonary TB in children with positive isolated TSTs should be made primarily with PA chest X-ray. A routine thoracic CT scan is not necessary for asymptomatic patients with only hilar lymphadenopathy findings in PA chest radiographs.

摘要

目的

探讨在结核菌素皮肤试验(TST)结果呈阳性、疑似肺结核(TB)的病例中,后前位(PA)胸部X线片和胸部计算机断层扫描(CT)检测到的阳性结果之间是否存在相关性。

方法

这是一项对2006年至2011年期间作为门诊患者就诊于伊斯坦布尔大学伊斯坦布尔医学院儿科学系且TST结果呈阳性(>15mm)的患者病历进行的回顾性评估。

结果

共有326例患者纳入研究;45.7%(n = 149)为女孩,平均年龄为9.0±4.1岁(范围:1 - 17岁)。总共有14.4%(n = 47)有结核病表现,均为肺门淋巴结肿大形式。在PA胸部X线片有结核病表现的47例病例中,45例(95.7%)在胸部CT中也有表现。尽管PA胸部X线片结果呈阳性,但只有2例(4.3%)患者胸部CT结果正常。

结论

对于单纯TST结果呈阳性的儿童,应主要通过PA胸部X线片评估肺结核。对于PA胸部X线片仅表现为肺门淋巴结肿大的无症状患者,常规胸部CT扫描没有必要。

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Arch Dis Child. 2013 Jun;98(6):401-4. doi: 10.1136/archdischild-2013-303672. Epub 2013 Apr 20.
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Global epidemiology of tuberculosis.全球结核病流行病学。
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Updated diagnosis and treatment of childhood tuberculosis.儿童结核病的诊治更新。
Imaging modalities for pulmonary tuberculosis in children: A systematic review.
儿童肺结核的影像学检查方法:一项系统评价
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How to optimize current (available) diagnostic tests.如何优化现有(可用)诊断测试。
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The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children.仅采用基于γ-干扰素释放试验的方法检测儿童潜伏性结核分枝杆菌感染的潜在风险。
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