Golden G S
Am J Dis Child. 1977 May;131(5):531-4. doi: 10.1001/archpedi.1977.02120180045008.
I report the clinical details of Tourette syndrome in 15 children. The condition typically starts at age 6 years with eyeblinking, and the child soon develops other tics and abnormal vocalizations. Coprolalia and echolalia occure but are infrequent. The average delay in correct diagnosis in this series was four years. Treatment with haloperidol produces a good or excellent response in three quarters of the patients. Many of the children have a history of encephalopathic events, "soft signs" on neurologic examination, and problems in school. Personal and social adjustmen are generally good, however.
我报告了15名儿童抽动秽语综合征的临床细节。该病通常始于6岁,以眨眼开始,患儿很快会出现其他抽动和异常发声。秽语症和模仿言语会出现,但不常见。该系列中正确诊断的平均延迟时间为四年。用氟哌啶醇治疗,四分之三的患者有良好或极佳的反应。许多儿童有脑病事件史、神经系统检查有“软体征”以及学习问题。然而,个人和社会适应能力总体良好。