鼠伤寒沙门氏菌毒力协同调控的证据，涉及95千碱基质粒的rsk元件。
Evidence of coordinate regulation of virulence in Salmonella typhimurium involving the rsk element of the 95-kilobase plasmid.
作者信息
Vandenbosch J L, Kurlandsky D R, Urdangaray R, Jones G W
机构信息
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109.
出版信息
Infect Immun. 1989 Aug;57(8):2566-8. doi: 10.1128/iai.57.8.2566-2568.1989.
Abstract
Integration of the Salmonella typhimurium virulence plasmid into the chromosome reduces mouse virulence, serum resistance, and HeLa cell adhesion-invasion while prolonging lag time in minimal medium. The proposed virulence plasmid regulatory element, rsk, partially restores virulence and fully restores the other three phenotypes to wild-type levels. Plasmid curing reduces virulence without affecting the other phenotypes. rsk has no apparent effect on the cured strain.
摘要
鼠伤寒沙门氏菌毒力质粒整合到染色体中会降低小鼠毒力、血清抗性以及HeLa细胞黏附-侵袭能力，同时延长在基本培养基中的延迟期。所提出的毒力质粒调控元件rsk可部分恢复毒力，并将其他三种表型完全恢复到野生型水平。质粒消除会降低毒力，但不影响其他表型。rsk对消除质粒的菌株没有明显影响。
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本文引用的文献
1
Rapid procedure for detection and isolation of large and small plasmids.用于检测和分离大小质粒的快速方法。
J Bacteriol. 1981 Mar;145(3):1365-73. doi: 10.1128/jb.145.3.1365-1373.1981.
2
P1 plasmid replication: replicon structure.P1质粒复制：复制子结构
J Mol Biol. 1984 Mar 5;173(3):307-24. doi: 10.1016/0022-2836(84)90123-2.
3
Genetic analysis of phase change in Bordetella pertussis.百日咳博德特氏菌相变的遗传分析。
Infect Immun. 1984 Jan;43(1):263-9. doi: 10.1128/iai.43.1.263-269.1984.
4
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter.启动子特异性转录因子Sp1与SV40早期启动子中的上游序列结合。
Cell. 1983 Nov;35(1):79-87. doi: 10.1016/0092-8674(83)90210-6.
5
Role of nine repeating sequences of the mini-F genome for expression of F-specific incompatibility phenotype and copy number control.F 小基因组的九个重复序列在 F 特异性不相容表型表达和拷贝数控制中的作用。
J Bacteriol. 1983 Jul;155(1):337-44. doi: 10.1128/jb.155.1.337-344.1983.
6
Sequence analysis of a region from the early right operon in phage P22 including the replication genes 18 and 12.噬菌体P22早期右操纵子中一个区域的序列分析，包括复制基因18和12。
Gene. 1984 Dec;32(3):289-303. doi: 10.1016/0378-1119(84)90004-0.
7
Bacteriophage lambda protein cII binds promoters on the opposite face of the DNA helix from RNA polymerase.噬菌体λ蛋白cII与DNA螺旋上与RNA聚合酶相对的那一面的启动子结合。
Nature. 1983;304(5928):703-8. doi: 10.1038/304703a0.
8
Association of adhesive, invasive, and virulent phenotypes of Salmonella typhimurium with autonomous 60-megadalton plasmids.鼠伤寒沙门氏菌的黏附、侵袭和毒力表型与自主的60兆道尔顿质粒的关联。
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9
The invasion of HeLa cells by Salmonella typhimurium: reversible and irreversible bacterial attachment and the role of bacterial motility.鼠伤寒沙门氏菌对海拉细胞的侵袭：细菌的可逆性和不可逆性附着以及细菌运动性的作用
J Gen Microbiol. 1981 Dec;127(2):351-60. doi: 10.1099/00221287-127-2-351.
10
Epidemiology of virulence-associated plasmids and outer membrane protein patterns within seven common Salmonella serotypes.七种常见沙门氏菌血清型中毒力相关质粒及外膜蛋白模式的流行病学研究
Infect Immun. 1985 Apr;48(1):175-82. doi: 10.1128/iai.48.1.175-182.1985.
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