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Preclinical and clinical studies with the hematopoietic colony-stimulating factors and related interleukins.

作者信息

Broxmeyer H E, Vadhan-Raj S

机构信息

Department of Medicine (Hematology/Oncology), Indiana University School of Medicine, Indianapolis.

出版信息

Immunol Res. 1989;8(3):185-201. doi: 10.1007/BF02918144.

DOI:10.1007/BF02918144
PMID:2664033
Abstract
摘要

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Preclinical and clinical studies with the hematopoietic colony-stimulating factors and related interleukins.造血集落刺激因子及相关白细胞介素的临床前和临床研究。
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Preclinical immunogenicity testing using anti-drug antibody analysis of GX-G3, Fc-fused recombinant human granulocyte colony-stimulating factor, in rat and monkey models.使用大鼠和猴模型中的抗药物抗体分析，对 GX-G3（Fc 融合重组人粒细胞集落刺激因子）进行临床前免疫原性测试。
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Study of stem cell homing & self-renewal marker gene profile of expanded human CD34 cells manipulated with a mixture of cytokines & stromal cell-derived factor 1.研究经细胞因子和基质细胞衍生因子 1 混合物处理的扩增人 CD34 细胞的干细胞归巢和自我更新标记基因特征。
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本文引用的文献

1
Production of lymphocyte-activating factor (Interleukin 1) by macrophages activated with colony-stimulating factors.集落刺激因子激活的巨噬细胞产生淋巴细胞激活因子（白细胞介素1）。
J Immunol. 1980 Sep;125(3):1302-5.
2
Endogenous regulation of macrophage proliferative expansion by colony-stimulating factor-induced interferon.集落刺激因子诱导的干扰素对巨噬细胞增殖性扩张的内源性调节
Science. 1984 Jan 13;223(4632):178-81. doi: 10.1126/science.6606850.
3
Colony assays of hematopoietic progenitor cells and correlations to clinical situations.造血祖细胞的集落分析及其与临床情况的相关性。
Genetic modification of ex-vivo expanded stem cells for clinical application.
临床应用的体外扩增干细胞的基因修饰。
Front Biosci (Landmark Ed). 2010 Jun 1;15(3):854-71. doi: 10.2741/3650.
4
Is interleukin 17, an inducible cytokine that stimulates production of other cytokines, merely a redundant player in a sea of other biomolecules?白细胞介素17是一种可诱导的细胞因子，能刺激其他细胞因子的产生，它仅仅是众多其他生物分子中的一个冗余角色吗？
J Exp Med. 1996 Jun 1;183(6):2411-5. doi: 10.1084/jem.183.6.2411.
5
Prediction of the role of granulocyte-macrophage colony-stimulating factor in animals and man from in vitro results.根据体外实验结果预测粒细胞巨噬细胞集落刺激因子在动物和人类中的作用。
Eur J Clin Microbiol Infect Dis. 1994;13 Suppl 2:S9-17. doi: 10.1007/BF01973596.
Crit Rev Oncol Hematol. 1984;1(3):227-57. doi: 10.1016/s1040-8428(84)80013-x.
4
Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: stimulation by endotoxin, M-CSF and multi-CSF.
Leuk Res. 1985;9(1):35-50. doi: 10.1016/0145-2126(85)90020-7.
5
Release from mouse macrophages of acidic isoferritins that suppress hematopoietic progenitor cells is induced by purified L cell colony stimulating factor and suppressed by human lactoferrin.纯化的L细胞集落刺激因子可诱导小鼠巨噬细胞释放抑制造血祖细胞的酸性异铁蛋白，而人乳铁蛋白则可抑制这种释放。
J Immunol. 1985 Nov;135(5):3224-31.
6
Erythropoietin coming of age.促红细胞生成素走向成熟。
N Engl J Med. 1987 Jan 8;316(2):101-3. doi: 10.1056/NEJM198701083160207.
7
In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor.重组人粒细胞集落刺激因子对粒细胞生成的体内刺激作用。
Proc Natl Acad Sci U S A. 1987 Apr;84(8):2484-8. doi: 10.1073/pnas.84.8.2484.
8
Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice.重组小鼠白细胞介素3、天然小鼠集落刺激因子-1和重组小鼠粒细胞-巨噬细胞集落刺激因子对小鼠骨髓生成的体内比较效应。
J Clin Invest. 1987 Mar;79(3):721-30. doi: 10.1172/JCI112877.
9
The influence in vivo of murine colony-stimulating factor-1 on myeloid progenitor cells in mice recovering from sublethal dosages of cyclophosphamide.
Blood. 1987 Mar;69(3):913-8.
10
Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial.用重组人促红细胞生成素纠正终末期肾病贫血。一项I期和II期联合临床试验的结果。
N Engl J Med. 1987 Jan 8;316(2):73-8. doi: 10.1056/NEJM198701083160203.