Broxmeyer H E, Vadhan-Raj S, Hangoc G, Lu L, Gutterman J U, Williams D E
Department of Medicine (Hematology/Oncology), Indiana University School of Medicine, Indianapolis.
Adv Exp Med Biol. 1988;241:233-41. doi: 10.1007/978-1-4684-5571-7_26.
Hematopoietic colony stimulating factors are available in purified recombinant form and have used for assessment of hematopoietic activities in mice, monkeys and in phase I clinical trials with humans. This report reviews the preclinical and clinical studies involving these factors.
造血集落刺激因子有纯化的重组形式,已用于评估小鼠、猴子的造血活性以及人类的I期临床试验。本报告回顾了涉及这些因子的临床前和临床研究。