Yue Junyan, Chen Jie, Dou Wenguang, Hu Ying, Li Qiang, Zhou Fengmei, Cui Hongkai, Wu Qingwu, Yang Ruimin
Imaging Center, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. China.
Exp Ther Med. 2015 Nov;10(5):1871-1876. doi: 10.3892/etm.2015.2768. Epub 2015 Sep 23.
The aim of the present study was to compare the accuracy of 64-multi-slice spiral computed tomography (64-MSCT) and 320-MSCT in the display of coronary artery stents and diagnosis of in-stent restenosis. The data collected from the 64- and 320-MSCT coronary angiography of 93 patients following coronary artery stent implantation were retrospectively analyzed. The 64-MSCT group comprised 30 cases with 57 stents and the 320-MSCT group comprised 63 cases with 93 stents. The image quality, heart rate of the patients and the radiation effective dose (ED) they were subjected to, were compared. Furthermore, the diagnostic abilities of 64-and 320-MSCT coronary angiography for in-stent restenosis were evaluated using invasive coronary angiography results as the gold standards. Statistically significant differences were observed in the heart rate and ED of the patients from the two groups (P<0.05), but no significant difference was identified in the accuracy index (P>0.05). The sensitivity, specificity, positive and negative predictive value and accuracy of the 64-MSCT group were found to be 100% (7/7), 93.94% (31/33), 77.78% (7/9), 100% (31/31) and 95% (38/40), respectively, and those in the 320-MSCT group were found to be 100% (16/16), 95.89% (70/73), 84.21% (16/19), 100% (70/70) and 96.63% (86/89), respectively. The present findings suggest that both 64-MSCT and 320-MSCT can be used for follow-up and curative effect evaluation following coronary stent implantation; however, 320-MSCT has fewer requirements of the patients' heart rate and uses a lower radiation dose.
本研究的目的是比较64层螺旋计算机断层扫描(64-MSCT)和320-MSCT在显示冠状动脉支架及诊断支架内再狭窄方面的准确性。回顾性分析93例冠状动脉支架植入术后患者的64-MSCT和320-MSCT冠状动脉造影数据。64-MSCT组30例,共57个支架;320-MSCT组63例,共93个支架。比较两组患者的图像质量、心率及所接受的辐射有效剂量(ED)。此外,以有创冠状动脉造影结果作为金标准,评估64-MSCT和320-MSCT冠状动脉造影对支架内再狭窄的诊断能力。两组患者的心率和ED差异有统计学意义(P<0.05),但准确性指标差异无统计学意义(P>0.05)。64-MSCT组的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为100%(7/7)、93.94%(31/33)、77.78%(7/9)、100%(31/31)和95%(38/40);320-MSCT组分别为100%(16/16)、95.89%(70/73)、84.21%(16/19)、100%(70/70)和96.63%(86/89)。本研究结果表明,64-MSCT和320-MSCT均可用于冠状动脉支架植入术后的随访及疗效评估;然而,320-MSCT对患者心率的要求较低,且辐射剂量更小。