Wegmann M, Fehrenbach H, Krauss-Etschmann S
Programmbereich Asthma & Allergie, Forschungszentrum Borstel, Leibniz-Zentrum für Medizin und Biowissenschaften, Airway Research Center North (ARCN), Mitglied des Deutschen Zentrums für Lungenforschung (DZL), Borstel.
Pneumologie. 2016 Feb;70(2):103-9. doi: 10.1055/s-0041-108313. Epub 2015 Dec 7.
Bronchial asthma is one of the most common chronic inflammatory diseases world-wide causing an enormous socio-economic burden especially in industrialized countries. Currently, asthma is increasingly considered to be a poly-symptomatic disease comprising a variety of different asthma phenotypes and endotypes. This heterogeneity of asthma explains why the standard treatment with corticosteroids and β-agonists cannot achieve full symptom control in all cases, especially not during acute exacerbations. Therefore, current asthma research focuses on primary prevention of asthma as well as on novel approaches towards a phenotype- and endotype-specific asthma therapy.
