Quyên Pham Thu, Pigeyre Marie, Caiazzo Robert, Verkindt Hélène, Deruelle Philippe, Pattou François
General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France.
General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France; Department of Nutrition - Obesity Unit, Huriez Hospital, Lille, France.
Surg Obes Relat Dis. 2015 Sep-Oct;11(5):1134-9. doi: 10.1016/j.soard.2015.03.015. Epub 2015 Mar 31.
Bariatric surgery is performed mostly on obese women of reproductive age. Many authors have studied pregnancy outcomes after bariatric surgery. Only a small number of studies have analyzed the impact of maternity on the results of bariatric surgery.
To study the effect of pregnancy on long-term outcomes of bariatric surgery.
Lille University Hospital.
A retrospective study was conducted on 591 women aged 18 to 42 years who had undergone laparoscopic adjustable gastric band (LAGB) surgery or laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery between 1996 and 2012. A comparison of the results after a 5-year follow-up was performed between patients who became pregnant after their bariatric surgery (pregnant group, n = 84) and postoperative nonpregnant women (nonpregnant group, n = 507).
At the 5-year visit, 84.8% patients were seen. The preoperative body mass index (BMI) was the same in the 2 groups (pregnant group: 47.8±6.9 kg/m(2); nonpregnant group: 47.5±7.2 kg/m(2); P = .755). The percentage of excess weight loss (%EWL) was lower in the pregnant group at 2 years (pregnant group = 45.9±24.6%; nonpregnant group = 56.9±28.6%, P = .002) but was similar at 5 years (47.7±27.7% versus 49.9±28.9%, P = .644). The decrease in co-morbidities was similar after 5 years. The gestational weight gain (GWG) was higher when the band was deflated during pregnancy (GWG =+12.7±10.5 kg) compared to the band without fluid removal (GWG =+4.9±7 kg) or laparoscopic Roux-en-Y gastric bypass (GWG =+4.4±1.1 kg) (P< .05).
Pregnancy after bariatric surgery slows down postoperative weight loss but does not affect weight results at 5-year follow-up.
减肥手术主要针对育龄肥胖女性进行。许多作者研究了减肥手术后的妊娠结局。只有少数研究分析了妊娠对减肥手术结果的影响。
研究妊娠对减肥手术长期结局的影响。
里尔大学医院。
对1996年至2012年间接受腹腔镜可调节胃束带（LAGB）手术或腹腔镜Roux-en-Y胃旁路术（LRYGB）手术的591名18至42岁女性进行回顾性研究。对减肥手术后怀孕的患者（怀孕组，n = 84）和术后未怀孕女性（未怀孕组，n = 507）进行5年随访后的结果比较。
在5年随访时，84.8%的患者接受了检查。两组术前体重指数（BMI）相同（怀孕组：47.8±6.9kg/m²；未怀孕组：47.5±7.2kg/m²；P = 0.755）。怀孕组在2年时的超重减轻百分比（%EWL）较低（怀孕组 = 45.9±24.6%；未怀孕组 = 56.9±28.6%，P = 0.002），但在5年时相似（47.7±27.7%对49.9±28.9%，P = 0.644）。5年后合并症的减少情况相似。与未排空束带（体重增加 = +4.9±7kg）或腹腔镜Roux-en-Y胃旁路术（体重增加 = +4.4±1.1kg）相比，怀孕期间束带放气时的孕期体重增加（GWG）更高（GWG = +12.7±10.5kg）（P < 0.05）。
减肥手术后怀孕会减缓术后体重减轻，但在5年随访时不影响体重结果。
