Barazzetti Lidiane, Pattussi Marcos Pascoal, Garcez Anderson da Silva, Mendes Karina Giane, Theodoro Heloísa, Paniz Vera Maria Vieira, Olinto Maria Teresa Anselmo
1Post-Graduate Program in Collective Health, University of Vale do Rio dos Sinos, São Leopoldo, Brazil 2University of Caxias do Sul, Caxias do Sul, Brazil 3Department of Nutrition, Federal University of Health Sciences, Porto Alegre, Brazil.
Menopause. 2016 Apr;23(4):433-40. doi: 10.1097/GME.0000000000000548.
This study investigated the association between minor psychiatric disorders and menopause symptoms and their associated factors.
A cross-sectional study was conducted with 615 women aged 40 to 65 years treated in a public menopause and gynecological outpatient clinic in the South Region of Brazil. Minor psychiatric disorders were assessed using the Self-Reporting Questionnaire (SRQ-20) and menopause symptoms using the Menopause Rating Scale. Score for menopause symptoms was categorized into three levels of symptoms: mild, moderate, and severe. Multivariate analyses used ordinal logistic regression.
The prevalence of mild, moderate, and severe menopause symptoms was 34.1% (95% CI 30.3-37.9), 29.6% (95% CI 25.8-33.1), and 36.3% (95% CI 32.4-40.0), respectively. The overall prevalence of minor psychiatric disorders was 66.6% (95% CI 62.8-70.3). After adjustment, the odds ratio (OR) of the occurrence of menopause symptoms were approximately eight times higher in women relating minor psychiatric disorders compared with those without such disorders (OR = 7.76; 95% CI 5.27-11.44). The following factors were also associated with the menopause symptoms: women older than 50 years, living with a partner, lower educational level, smokers, larger number of pregnancies, obese, and those using psychotropic and/or postmenopause medication.
The minor psychiatric disorders exhibited strong association with the presence of menopause symptoms independently of sociodemographic, behavioral, and reproductive factors, and of use of psychotropic medication.
本研究调查了轻度精神障碍与更年期症状及其相关因素之间的关联。
对在巴西南部地区一家公共更年期和妇科门诊接受治疗的615名40至65岁女性进行了横断面研究。使用自填问卷（SRQ - 20）评估轻度精神障碍，使用更年期评定量表评估更年期症状。更年期症状评分分为轻度、中度和重度三个症状级别。多变量分析采用有序逻辑回归。
轻度、中度和重度更年期症状的患病率分别为34.1%（95%置信区间30.3 - 37.9）、29.6%（95%置信区间25.8 - 33.1）和36.3%（95%置信区间32.4 - 40.0）。轻度精神障碍的总体患病率为66.6%（95%置信区间62.8 - 70.3）。调整后，患有轻度精神障碍的女性出现更年期症状的比值比（OR）约为未患此类障碍女性的八倍（OR = 7.76；95%置信区间5.27 - 11.44）。以下因素也与更年期症状相关：50岁以上的女性、有伴侣、教育水平较低、吸烟者、怀孕次数较多、肥胖以及使用精神药物和/或绝经后药物的女性。
轻度精神障碍与更年期症状的存在表现出强烈关联，独立于社会人口学、行为和生殖因素以及精神药物的使用。
