Ossowski A, Kuś M, Kupiec T, Bykowska M, Zielińska G, Jasiński M E, March A L
Department of Forensic Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Department of Forensic Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Forensic Sci Int. 2016 Jan;258:41-9. doi: 10.1016/j.forsciint.2015.10.029. Epub 2015 Nov 30.
This paper describes the creation of the Polish Genetic Database of Victims of Totalitarianism and the first research conducted under this project. On September 28th 2012, the Pomeranian Medical University in Szczecin and the Institute of National Remembrance-Commission for Prosecution of Crimes against the Polish Nation agreed to support the creation of the Polish Genetic Database of Victims of Totalitarianism (PBGOT, www.pbgot.pl). The purpose was to employ state-of-the-art methods of forensic genetics to identify the remains of unidentified victims of Communist and Nazi totalitarian regimes. The database was designed to serve as a central repository of genetic information of the victim's DNA and that of the victim's nearest living relatives, with the goal of making a positive identification of the victim. Along the way, PGBOT encountered several challenges. First, extracting useable DNA samples from the remains of individuals who had been buried for over half a century required forensic geneticists to create special procedures and protocols. Second, obtaining genetic reference material and historical information from the victim's closest relatives was both problematic and urgent. The victim's nearest living relatives were part of a dying generation, and the opportunity to obtain the best genetic and historical information about the victims would soon die with them. For this undertaking, PGBOT assembled a team of historians, archaeologists, forensic anthropologists, and forensic geneticists from several European research institutions. The field work was divided into five broad categories: (1) exhumation of victim remains and storing their biological material for later genetic testing; (2) researching archives and historical data for a more complete profile of those killed or missing and the families that lost them; (3) locating the victim's nearest relatives to obtain genetic reference samples (swabs), (4) entering the genetic data from both victims and family members into a common database; (5) making a conclusive, final identification of the victim. PGBOT's first project was to identify victims of the Communist regime buried in hidden mass graves in the Powązki Military Cemetery in Warsaw. Throughout 2012 and 2013, PGBOT carried out archaeological exhumations in the Powązki Military Cemetery that resulted in the recovery of the skeletal remains of 194 victims in several mass graves. Of the 194 sets of remains, more than 50 victims have been successfully matched and identified through genetic evidence.
本文介绍了波兰极权主义受害者基因数据库的创建以及该项目下开展的首次研究。2012年9月28日,什切青的波美拉尼亚医科大学与国家纪念研究所——波兰民族罪行起诉委员会达成协议,支持创建波兰极权主义受害者基因数据库(PBGOT,www.pbgot.pl)。其目的是运用法医遗传学的先进方法,识别共产主义和纳粹极权政权下身份不明受害者的遗体。该数据库旨在作为受害者DNA及其在世近亲DNA的基因信息中央存储库,目标是对受害者进行确定性身份鉴定。在此过程中,PGBOT遇到了几个挑战。首先,从埋葬了半个多世纪的个体遗体中提取可用的DNA样本,要求法医遗传学家制定特殊的程序和方案。其次,从受害者最亲近的亲属那里获取基因参考材料和历史信息既存在问题又十分紧迫。受害者在世的近亲属于行将消逝的一代人,获取有关受害者最佳基因和历史信息的机会将很快随他们一同消逝。为此,PGBOT组建了一个由来自几个欧洲研究机构的历史学家、考古学家、法医人类学家和法医遗传学家组成的团队。实地工作分为五大类:(1)挖掘受害者遗体并存储其生物材料以供后续基因检测;(2)研究档案和历史数据,以更全面地了解那些被杀或失踪者以及失去他们的家庭情况;(3)找到受害者最亲近的亲属以获取基因参考样本(拭子);(4)将受害者和家庭成员的基因数据录入一个通用数据库;(5)对受害者进行确定性的最终身份鉴定。PGBOT的首个项目是识别埋葬在华沙Powązki军事公墓秘密乱葬坑中的共产主义政权受害者。在2012年至2013年期间,PGBOT在Powązki军事公墓进行了考古挖掘,从几个乱葬坑中找到了194名受害者的遗骸。在这194套遗骸中,已有50多名受害者通过基因证据成功比对并确认了身份。