Sanhal Cem Yasar, Mendilcioglu Inanc, Ozekinci Murat, Simsek Mehmet, Bozkurt Selen
Cem Yasar Sanhal, MD. Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.
Inanc Mendilcioglu, Professor, Gynecology and Obstetrics Department, Akdeniz University Faculty of Medicine, Antalya, Turkey.
Pak J Med Sci. 2015 Sep-Oct;31(5):1038-42. doi: 10.12669/pjms.315.7477.
To compare the pre-procedural anxiety and depression levels of patients undergoing chorion villus sampling (CVS) and amniocentesis (AC).
Patients referred to our department for fetal karyotype analysis with a positive first or second trimester screening test for aneuploidy between January 2013 to June 2015 were included. CVS and AC procedures were performed in patients with gestation periods of between 11-14 and 16-20 weeks, respectively. Anxiety was evaluated using the Spielberger State-Trait Anxiety Inventory (STAI), and depression was assessed using the Beck Depression Inventory II (BDI-II).
A total of 1,400 patients were included. Compared to first trimester controls, patients undergoing CVS had significantly higher STAI-state and BDI-II results. Likewise, patients undergoing AC had higher STAI-state and BDI-II scores than controls in the second trimester. In terms of STAI-trait results, no difference was found between the groups. Our results also showed that, compared to AC group, patients undergoing CVS had similar STAI-state, STAI-trait and but higher BDI-II scores.
We conclude that evaluating the stress and depression levels of these patients should be one of the routine procedures in pregnancy follow-up.
比较接受绒毛取样（CVS）和羊膜穿刺术（AC）的患者术前焦虑和抑郁水平。
纳入2013年1月至2015年6月期间因孕早期或孕中期非整倍体筛查试验阳性而转诊至我科进行胎儿核型分析的患者。分别对妊娠11 - 14周和16 - 20周的患者进行CVS和AC操作。使用斯皮尔伯格状态 - 特质焦虑量表（STAI）评估焦虑，使用贝克抑郁量表第二版（BDI-II）评估抑郁。
共纳入1400例患者。与孕早期对照组相比，接受CVS的患者STAI状态和BDI-II结果显著更高。同样，接受AC的患者在孕中期的STAI状态和BDI-II评分高于对照组。在STAI特质结果方面，各组之间未发现差异。我们的结果还表明，与AC组相比，接受CVS的患者STAI状态、STAI特质相似，但BDI-II评分更高。
我们得出结论，评估这些患者的应激和抑郁水平应成为孕期随访的常规程序之一。
