Kett K
Tidsskr Nor Laegeforen. 1989 Jun 30;109(19-21):2037.
IgA-specific microbial proteases possess the ability to reduce the protective effects of secretory IgA antibodies. The fact that fungi such as Candida produce both IgA1-and IgA2-specific proteases has not been acknowledged in articles and discussions concerning the chronic Candida syndrome. Therefore a short survey of these interesting proteases is presented, along with hypotheses concerning alterations IgA fragments may induce in immunoregulation and uptake of antigens from the gut.
IgA特异性微生物蛋白酶具有降低分泌型IgA抗体保护作用的能力。在关于慢性念珠菌综合征的文章和讨论中,尚未提及念珠菌等真菌会产生IgA1和IgA2特异性蛋白酶这一事实。因此,本文简要介绍了这些有趣的蛋白酶,并提出了关于IgA片段可能在免疫调节和肠道抗原摄取方面引起改变的假说。