Rüchel R
Department of Medical Microbiology, University of Göttingen, FRG.
Microbiol Sci. 1986 Oct;3(10):316-9.
The yeast-like fungi Candida albicans and Candida tropicalis are opportunistic pathogens which are distinguished from less virulent yeasts by the secretion of acid proteases. Candida proteases cleave various human immunoglobulins including IgA2 and secretory immunoglobulins. They cover a wider range of substrates than bacterial IgA-proteases, and possibly play a role in the pathogenesis of thrush and deep candidosis.
酵母样真菌白色念珠菌和热带念珠菌是机会致病菌，它们通过分泌酸性蛋白酶与毒力较弱的酵母相区别。念珠菌蛋白酶可裂解多种人类免疫球蛋白，包括IgA2和分泌型免疫球蛋白。与细菌IgA蛋白酶相比，它们的底物范围更广，可能在鹅口疮和深部念珠菌病的发病机制中起作用。
