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[中国国家自然科学基金资助的移植生物学研究项目回顾与分析]

[Review and analysis of transplant biological research projects funded by National Natural Science Foundation of China].

作者信息

Gong Weihua, Sun Ruijuan, Dong Erdan

机构信息

Department of Health Sciences, National Natural Science Foundation of China, Beijing 100085, China.

Department of Health Sciences, National Natural Science Foundation of China, Beijing 100085, China; Email:

出版信息

Zhonghua Wai Ke Za Zhi. 2015 Aug 1;53(8):622-7.

Abstract

OBJECTIVE

To study the funding and achievements in the field of organ transplantation support by the National Natural Science Foundation of China (NSFC).

METHODS

A search of NSFC database was made by using the key word "transplantation" and excluding "bone marrow transplantation" for the projects funded between 1988 and 2013. SCI indexed publications that marked with NSFC project number were collected by searching each grant number in the database of the Web of Science.

RESULTS

Six hundreds fifty-five projects were identified and received about 220 million yuan in grant funding. These funded research projects were distributed among 25 provinces and autonomous regions, however, which were mainly in the developed coastal areas; of them, 43 (6.56%) projects were granted in xenotransplantation and 17 projects (2.60%) were funded in the field of traditional Chinese medicine-related organ transplantation; Transplantation on blood vessels, heart, kidney, liver, lung, small intestine, pancreatic, cornea, trachea, skin, etc. were primarily performed in research. Nine hundreds and sixty-one SCI-indexed publications were achieved.

CONCLUSIONS

Magnitude and intensity of NSFC funding, output of SCI publications have been increasing, suggesting that NSFC positively promotes the development of organ transplantation. Although a great progress of transplantation has been made, basic and translational studies should be vigorously strengthened.

摘要

目的

研究国家自然科学基金(NSFC)在器官移植支持领域的资助情况与成果。

方法

通过在NSFC数据库中检索关键词“移植”,并排除“骨髓移植”,筛选出1988年至2013年间资助的项目。通过在Web of Science数据库中搜索每个资助编号,收集标注有NSFC项目编号的SCI索引出版物。

结果

共识别出655个项目,获得约2.2亿元的资助资金。这些资助的研究项目分布在25个省和自治区,但主要集中在沿海发达地区;其中,43个(6.56%)项目获得异种移植资助,17个(2.60%)项目获得与中医相关器官移植领域的资助;血管、心脏、肾脏、肝脏、肺、小肠、胰腺、角膜、气管、皮肤等的移植是主要的研究方向。共发表961篇SCI索引出版物。

结论

NSFC的资助规模和强度、SCI出版物的产出一直在增加,表明NSFC对器官移植的发展起到了积极的推动作用。虽然移植领域已取得巨大进展,但基础研究和转化研究仍应大力加强。

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