[药物不良反应——定义、风险因素及药物警戒]

[Adverse drug reaction - Definitions, risk factors and pharmacovigilance].

作者信息

Krähenbühl Stephan

机构信息

1 Klinische Pharmakologie & Toxikologie, Universitätsspital Basel.

出版信息

Ther Umsch. 2015 Dec;72(11-12):669-71. doi: 10.1024/0040-5930/a000735.

DOI:10.1024/0040-5930/a000735

PMID:26654809

Abstract

Adverse drug reactions (ADR} are the downside of active pharmacotherapies and can only partially be avoided. Risk factors have been identified for certain ADR which should be taken into account for the choice and dosing of critical drugs. Medical staff have a legal obligation to report severe ADR and ADR caused by newly licensed drugs. Such reports are important for monitoring the safety of drugs that are on the market.

摘要

药物不良反应（ADR）是活性药物治疗的负面效应，只能部分避免。已确定某些药物不良反应的风险因素，在选择关键药物和确定其剂量时应予以考虑。医务人员有法律义务报告严重的药物不良反应以及由新获批药物引起的药物不良反应。此类报告对于监测上市药物的安全性至关重要。