Alawneh Alia, Yasin Hesham, Khirfan Ghaleb, Qayas Bashar Abu, Ammar Khawla, Rimawi Dalia, Klepstad Pål
Palliative Medicine Department, King Hussein Cancer Center, Queen Rania street, Amman, Jordan.
Internal Medicine Department, King Hussein Cancer Center, Amman, Jordan.
Support Care Cancer. 2016 Jun;24(6):2455-62. doi: 10.1007/s00520-015-3018-9. Epub 2015 Dec 11.
Health related quality of life (HRQOL) is an important outcome in cancer care and needs assessment by a valid questionnaire. HRQOL questionnaires need to be validated after translations to other languages and cultural settings. The purpose of this study is to evaluate the psychometric properties of the Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life 15 items Questionnaire for Palliative Care (EORTC QLQ-C15-PAL).
This is a cross-sectional study of a convenient sample of inpatients with cancer.
One hundred seventy-five patients completed the EORTC QLQ-C15-PAL questionnaire. Cronbach's alpha coefficient met the 0.7 alpha criterion. Confirmatory factor analysis met the goodness of fit criteria; goodness-of-fit index (GFI), comparative fit index (CFI), normed fit index (NFI) and non-normed fit index (NNFI) >0.90 and root mean square error of approximation (RMSEA) <0.06. All item-scale correlation coefficients exceeded the set value of 0.40, indicating satisfactory convergent validity. In terms of discriminant validity, all items in the questionnaire showed a higher item-scale correlation than item-other scale correlation, except for items 1 and 2 (physical function scale) that showed a higher correlation with fatigue. Construct validity was tested by item inter scale correlation coefficient. All constructs had correlation coefficient <0.70. External validity was tested by comparison of scores of patients who had metastasis and who did not have metastasis. Significant differences (P value <0.05) were found in all scales except for nausea. Age groups were compared and showed significant differences for physical function, fatigue, and global score of HRQOL.
The Arabic version of the EORTC QLQ-C15-PAL is valid and reliable.
健康相关生活质量（HRQOL）是癌症护理中的一项重要结果，需要通过有效的问卷进行评估。HRQOL问卷在翻译成其他语言和文化背景后需要进行验证。本研究的目的是评估欧洲癌症研究与治疗组织姑息治疗生活质量15项问卷（EORTC QLQ-C15-PAL）阿拉伯语版本的心理测量特性。
这是一项对癌症住院患者便利样本的横断面研究。
175名患者完成了EORTC QLQ-C15-PAL问卷。克朗巴哈系数满足0.7的标准。验证性因子分析符合拟合优度标准；拟合优度指数（GFI）、比较拟合指数（CFI）、规范拟合指数（NFI）和非规范拟合指数（NNFI）>0.90，近似均方根误差（RMSEA）<0.06。所有项目与量表的相关系数均超过设定值0.40，表明具有令人满意的收敛效度。在区分效度方面，问卷中的所有项目与量表的相关性均高于与其他量表的相关性，但项目1和2（身体功能量表）与疲劳的相关性较高。通过项目间量表相关系数检验结构效度。所有结构的相关系数<0.70。通过比较有转移和无转移患者的得分来检验外部效度。除恶心外，所有量表均发现显著差异（P值<0.05）。比较年龄组，发现身体功能、疲劳和HRQOL总体得分存在显著差异。
EORTC QLQ-C15-PAL阿拉伯语版本有效且可靠。
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