Institute of Applied Sciences and Intelligent System (CNR-ISASI), Italy.
Institute for Microelectronics and Microsystems (CNR-IMM), Italy.
Lab Chip. 2016 Jan 21;16(2):326-33. doi: 10.1039/c5lc01386k.
We report a novel method for direct printing of viscous polymers based on a pyro-electrohydrodynamic repulsion system capable of overcoming limitations on the material type, geometry and thickness of the receiving substrate. In fact, the results demonstrate that high viscosity polymers can be easily manipulated for optical functionalizing of lab-on-a-chip devices through demonstration of direct printing of polymer microlenses onto microfluidic chips and optical fibre terminations. The present system has great potential for applications from biomolecules to nano-electronics. Moreover, in order to prove the effectiveness of the system, the optical performance of such microlenses has been characterized by testing their imaging capabilities when the fibroblast cells were allowed to flow inside the microfluidic channel, showing one of their possible applications on-board a LoC platform.
我们报告了一种基于热机电排斥系统的新型粘性聚合物直接打印方法,该方法能够克服接收基底的材料类型、几何形状和厚度的限制。事实上,研究结果表明,通过在微流控芯片和光纤末端上直接打印聚合物微透镜,可轻松对高粘度聚合物进行操控,以实现芯片上实验室的光学功能化。该系统在从生物分子到纳米电子学的应用方面具有很大的潜力。此外,为了证明该系统的有效性,我们通过测试当成纤维细胞在微流道内流动时这些微透镜的成像能力,对其光学性能进行了表征,展示了其在 LoC 平台上的一种可能的应用。