阿片类药物依赖综合征中丁丙诺啡维持治疗的依从性：一项病例对照研究。
Adherence to Buprenorphine Maintenance Treatment in Opioid Dependence Syndrome: A Case Control Study.
作者信息
Bandawar Mrunal, Kandasamy Arun, Chand Prabhat, Murthy Pratima, Benegal Vivek
机构信息
Department of Clinical Neurosciences, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Assistant Professor of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
出版信息
Indian J Psychol Med. 2015 Jul-Sep;37(3):330-2. doi: 10.4103/0253-7176.162951.
BACKGROUND
Opioid Use disorders are emerging as a serious public health concern in India. Opioid substitution treatment is one of the emerging forms of treatment in this population which needs more evidence to increase its availability and address prejudices towards the same.
MATERIALS AND METHODS
This is a case control study with retrospective design reviewing the charts of patients with opioid dependence syndrome registered between January 2005 to December 2012. Adherence to treatment was the outcome variable assessed in this study.
RESULTS
The odds of the Buprenorphine Maintenance Treatment (BMT) group remaining in treatment is 4.5 (P < 0.005) times more than Naltrexone Maintenance Treatment (NMT) group and 7 times (P < 0.001) more than Psychosocial intervention (PST) alone group.
DISCUSSION
We believe that these study findings will help in reducing the prejudice towards BMT and encourage further research in this field.
CONCLUSION
BMT has a better adherence rate than other treatments in opioid use disorders.
背景
在印度，阿片类物质使用障碍正成为一个严重的公共卫生问题。阿片类物质替代治疗是该人群中新兴的治疗形式之一，需要更多证据来提高其可及性并消除对其的偏见。
材料与方法
这是一项回顾性设计的病例对照研究，回顾了2005年1月至2012年12月期间登记的阿片类物质依赖综合征患者的病历。本研究评估的结局变量是治疗依从性。
结果
丁丙诺啡维持治疗（BMT）组持续接受治疗的几率是纳曲酮维持治疗（NMT）组的4.5倍（P < 0.005），是单纯心理社会干预（PST）组的7倍（P < 0.001）。
讨论
我们认为这些研究结果将有助于减少对BMT的偏见，并鼓励在该领域进行进一步研究。
结论
在阿片类物质使用障碍中，BMT的依从率高于其他治疗方法。
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