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取决于无机锌化合物浓度的氧化应激变化参数。

Parameters of oxidative stress variation depending on the concentration of inorganic zinc compounds.

作者信息

Grigorescu R, Gruia M I, Nacea V, Nitu C

机构信息

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

"Prof. Dr. Alex. Trestioreanu" Oncological Institute, Bucharest, Romaniaa.

出版信息

J Med Life. 2015 Oct-Dec;8(4):449-51.

PMID:26664468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4656950/
Abstract

Zinc deficiency is a problem faced by a large number of people, a U.S. study showing that only 46% of the population aged over 71 years has the best amount of zinc in the body. Due to the very complex role of zinc deficiency in this trace, it can occur through a variety of symptoms affecting multiple body functions. Zinc was demonstrated to have the ability to neutralize free radicals protecting the body from the harmful effects of these effects, ultimately leading to atherosclerosis and cardiovascular disease derived from premature aging, the immune and immune disorders and increased risk of cancer. The purpose of the paper is to identify the role of antioxidant systems, with Zn2+ ions in the center of defense and decrease oxidative stress in dynamic interaction with malignant transformed cells.

摘要

锌缺乏是大量人群面临的一个问题,一项美国研究表明,71岁以上的人群中只有46%体内的锌含量处于最佳水平。由于锌这种微量元素缺乏所起的作用非常复杂,它会通过影响多种身体功能的各种症状表现出来。锌被证明有能力中和自由基,保护身体免受这些自由基的有害影响,这些影响最终会导致动脉粥样硬化和源自过早衰老的心血管疾病、免疫和免疫紊乱以及癌症风险增加。本文的目的是确定抗氧化系统的作用,其中以Zn2+离子为防御核心,并在与恶性转化细胞的动态相互作用中降低氧化应激。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/611e005bf9fb/JMedLife-08-449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/dd6648d3d936/JMedLife-08-449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/7e551c7c37a3/JMedLife-08-449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/611e005bf9fb/JMedLife-08-449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/dd6648d3d936/JMedLife-08-449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/7e551c7c37a3/JMedLife-08-449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f9/4656950/611e005bf9fb/JMedLife-08-449-g003.jpg

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引用本文的文献

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本文引用的文献

1
The oxidative stress of zinc deficiency.锌缺乏的氧化应激。
Metallomics. 2011 Nov;3(11):1124-9. doi: 10.1039/c1mt00064k. Epub 2011 Jul 26.
2
Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in rats.锌缺乏会影响大鼠的DNA损伤、氧化应激、抗氧化防御和DNA修复。
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Zinc content of normal human serum and its correlation with some hematic parameters.正常人血清锌含量及其与某些血液学参数的相关性。
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