Slaoui Amine, Jabbour Youness, El Ghazoui Anouar, Karmouni Tarik, Elkhader Khalid, Koutani Abdelatif, Attaya Ahmed Ibn
Urology B, Ibn Sina University Hospital, Rabat, Morocco.
Pan Afr Med J. 2015 Sep 18;22:53. doi: 10.11604/pamj.2015.22.53.6563. eCollection 2015.
The aim of our study was to report the status of penile cancer sites in the urology department at the University Hospital of Rabat and evaluate long-term results of surgical treatment of this cancer.
Between 1989 and 2015, 10 patients were treated for penile cancer. 10 cases were retrospectively reviewed and the following data were recorded: mode of revelation, seat, staging, TNM stage, treatment, evolution and survival. The mean age of patients was 58,1 years (48-81 years). All patients had squamous cell carcinoma of the penis. Six patients had a partial amputation of the penis, and three patients underwent total amputation. The median size of the lesion was 4.25 cm (1.5-8 cm). All tumors had a distal seat (gland- Furrow balanopreputial), 8 were localized and non-invasive (PT1 - PT2) and 2 had infiltrated the urethra (PT3). Four patients had lymph node localization. A single bilateral lymphadenectomy was performed and was positive only on one side, with a node <3 cm and no extracapsular extension. Two patients were referred for chemotherapy, a neoadjuvant referred to basic (Bleomycin - Methotrexate, Cisplatin) the other in a palliative goal. Median follow-up was 42 months (6 -72mois). Four patients died, one of which was presented immediately with metastatic mode. Six patients were alive at last node or local recurrence negative. Cancer of the penis seems rare in Morocco. His oncologic and functional outcomes (sexual and urinary) depend on the precocity of the treatment. The surgery of lymph node resection with lymphadenectomy remains the reference treatment.
我们研究的目的是报告拉巴特大学医院泌尿外科阴茎癌的发病部位状况,并评估该癌症手术治疗的长期结果。
1989年至2015年间,10例患者接受了阴茎癌治疗。对10例病例进行回顾性分析,并记录以下数据:发病方式、部位、分期、TNM分期、治疗、病情演变及生存情况。患者的平均年龄为58.1岁(48 - 81岁)。所有患者均为阴茎鳞状细胞癌。6例患者接受了阴茎部分切除术,3例患者接受了阴茎全切术。病变的中位大小为4.25厘米(1.5 - 8厘米)。所有肿瘤均位于远端(龟头 - 冠状沟包皮),8例为局限性且无浸润(PT1 - PT2),2例浸润了尿道(PT3)。4例患者有淋巴结转移。仅进行了一次双侧淋巴结清扫术,仅一侧呈阳性,淋巴结<3厘米且无包膜外扩展。2例患者接受了化疗,1例为新辅助化疗(使用博来霉素 - 甲氨蝶呤、顺铂),另1例为姑息性化疗。中位随访时间为42个月(6 - 72个月)。4例患者死亡,其中1例以转移方式就诊。6例患者在最后一次随访时存活,无局部复发。阴茎癌在摩洛哥似乎较为罕见。其肿瘤学和功能结局(性和尿功能)取决于治疗的及时性。淋巴结清扫术仍然是标准治疗方法。