Department of Clinical Science, National Hospital Organization Okayama Medical Center , Okayama , Japan.
Front Cardiovasc Med. 2015 Feb 17;2:4. doi: 10.3389/fcvm.2015.00004. eCollection 2015.
In chronic thromboembolic pulmonary hypertension (CTEPH), stenoses or obstructions of the pulmonary arteries due to organized thrombi can cause an elevation in pulmonary artery resistance, which in turn can result in pulmonary hypertension. CTEPH can be cured surgically by pulmonary endarterectomy (PEA); however, patients deemed unsuitable for PEA due to lesion, advanced age, or comorbidities have a poor prognosis and limited treatment options. Recently, advances have been made in balloon pulmonary angioplasty for these patients, and this review highlights this recent progress.
在慢性血栓栓塞性肺动脉高压(CTEPH)中,由于血栓形成导致的肺动脉狭窄或阻塞可引起肺动脉阻力升高,进而导致肺动脉高压。CTEPH 可以通过肺动脉内膜切除术(PEA)进行手术治愈;然而,由于病变、年龄较大或合并症等原因而不适合进行 PEA 的患者预后较差,治疗选择有限。最近,在这些患者的球囊肺动脉成形术方面取得了进展,本综述重点介绍了这一最新进展。