Zakharova I B, Viktorov D V
Mol Gen Mikrobiol Virusol. 2015;33(3):9-16.
Integrative conjugative elements (ICEs) are an extensive group of mobile genetic elements found in the Gram-positive and Gram-negative bacteria. These genetic elements are replicated being incorporated into host chromosome, but retain the ability for excision and conjugative transfer. Given a set of the genes of the conjugative transfer, control of removal and integration, ICEs are directly involved in the processes of horizontal transfer of genetic determinants, which increase the adaptive potential of the bacterial species, as well as act as a mobilizing factor for other genetic elements.
整合型接合元件(ICEs)是在革兰氏阳性菌和革兰氏阴性菌中发现的一类广泛的可移动遗传元件。这些遗传元件在整合到宿主染色体中时进行复制,但保留了切除和接合转移的能力。鉴于存在一组接合转移、切除和整合控制的基因,ICEs直接参与遗传决定因素的水平转移过程,这增加了细菌物种的适应潜力,并且还作为其他遗传元件的移动因子。