Bernal Sahagún F, Barinagarrementería A R, Barrera Ríos L, Briseño Velazco S, Casillas Romo A, Corral Medina A, De la Torre Bravo A, Díaz de León E, Díaz Seoane R, Gallo Reynoso S
Rev Gastroenterol Mex. 1989 Jan-Mar;54(1):13-7.
A multicenter open study aimed at evaluating the effect of famotidine in the treatment of duodenal ulcer was performed in several institutions located in 15 different cities of Mexico. One-hundred-and-fourteen patients with duodenal ulcer demonstrated by endoscopy were given 40 mg. of famotidine daily, administered as a single dose at night. After 4 and 6 weeks of treatment, healing of the ulcer was observed in 81.6% and 95.6% of patients, respectively. Side-effects were very unusual. In only one patient, who experienced vertigo during the treatment, administration of the drug had to be stopped.
在墨西哥15个不同城市的多家机构进行了一项多中心开放性研究，旨在评估法莫替丁治疗十二指肠溃疡的效果。114例经内镜证实为十二指肠溃疡的患者，每天给予40毫克法莫替丁，于夜间单次给药。治疗4周和6周后，分别有81.6%和95.6%的患者溃疡愈合。副作用非常罕见。仅1例患者在治疗期间出现眩晕，不得不停药。
