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CD248/Endosialin: A Novel Pericyte Target in Renal Fibrosis.

作者信息

Chang-Panesso Monica, Humphreys Benjamin D

出版信息

Nephron. 2015;131(4):262-4. doi: 10.1159/000440890. Epub 2015 Dec 11.

Abstract
摘要

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本文引用的文献

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Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.
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Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies.
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Cell Stem Cell. 2015 Jan 8;16(1):51-66. doi: 10.1016/j.stem.2014.11.004. Epub 2014 Nov 20.
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A first-in-human phase I study of MORAb-004, a monoclonal antibody to endosialin in patients with advanced solid tumors.
Clin Cancer Res. 2015 Mar 15;21(6):1281-8. doi: 10.1158/1078-0432.CCR-14-1829. Epub 2014 Nov 14.
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A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.
N Engl J Med. 2014 May 29;370(22):2083-92. doi: 10.1056/NEJMoa1402582. Epub 2014 May 18.
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Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis.
N Engl J Med. 2014 May 29;370(22):2071-82. doi: 10.1056/NEJMoa1402584. Epub 2014 May 18.
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PDGF and the progression of renal disease.
Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i45-i54. doi: 10.1093/ndt/gft273.
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CD248+ stromal cells are associated with progressive chronic kidney disease.
Kidney Int. 2011 Jul;80(2):199-207. doi: 10.1038/ki.2011.103. Epub 2011 Apr 13.

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