Samier-Guérin Anne, Saraux Alain, Gestin Simon, Cornec Divi, Marhadour Thierry, Devauchelle-Pensec Valérie, Bressollette Luc, Nonent Michel, Jousse-Joulin Sandrine
Service de radiologie, CHU de la Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest, France.
Service de rhumatologie, CHU de la Cavale-Blanche, boulevard Tanguy-Prigent, 29609 Brest, France; EA 2216, université Bretagne-Occidentale, BP 824, 29200 Brest, France.
Joint Bone Spine. 2016 May;83(3):301-6. doi: 10.1016/j.jbspin.2015.11.002. Epub 2015 Dec 8.
The diagnosis of primary Sjögren's syndrome (pSS) rests on a converging set of clinical and laboratory findings. Salivary-gland ultrasonography (SGUS) was recently shown to assist in the diagnosis and therapeutic monitoring of pSS. Our objective here was to measure salivary-gland elasticity using Acoustic Radiation Force Impulse (ARFI) ultrasonography in patients with pSS and to compare the results to those obtained in healthy controls.
SGUS with ARFI elastometry was performed in 10 patients with pSS and 15 healthy controls. Ten impulses per gland were used for both submandibular and both parotid glands of each participant. Mean shear wave velocity (SWV) in m/s was compared between the patients and controls using the Mann-Whitney U test.
For the parotid glands, mean SWV was significantly higher in the pSS group than in the control group (2.335±0.315 vs 1.785±0.384, respectively; P=0.001). Mean SWV values for the submandibular glands were not significantly different between the patients and controls (1.812±0.308 vs 1.766±0.187, respectively; P=0.892).
ARFI elastometry may contribute to the diagnosis of pSS, as this noninvasive, fast, and inexpensive investigation can demonstrate abnormal architectural changes in the parotid glands.
原发性干燥综合征（pSS）的诊断基于一系列综合的临床和实验室检查结果。唾液腺超声检查（SGUS）最近被证明有助于pSS的诊断和治疗监测。我们的目的是使用声辐射力脉冲（ARFI）超声检查测量pSS患者的唾液腺弹性，并将结果与健康对照者的结果进行比较。
对10例pSS患者和15名健康对照者进行了带有ARFI弹性成像的SGUS检查。对每个参与者的双侧下颌下腺和双侧腮腺，每个腺体使用10次脉冲。使用Mann-Whitney U检验比较患者和对照者之间以米/秒为单位的平均剪切波速度（SWV）。
对于腮腺，pSS组的平均SWV显著高于对照组（分别为2.335±0.315和1.785±0.384；P=0.001）。患者和对照者下颌下腺的平均SWV值无显著差异（分别为1.812±0.308和1.766±0.187；P=0.892）。
ARFI弹性成像可能有助于pSS的诊断，因为这种无创、快速且廉价的检查可以显示腮腺的异常结构变化。
