Department of Oral Radiology, Minia University, Minia, Egypt.
Dentomaxillofac Radiol. 2020 Mar;49(3):20190225. doi: 10.1259/dmfr.20190225. Epub 2019 Nov 28.
The aim of this study was to assess chronic inflammatory conditions of major salivary glands by ultrasound elastography.
21 patients with chronic inflammatory conditions of major salivary glands and 21 healthy adult volunteers were included in this study. All participants underwent B-mode sonography and ultrasound elastography. The diagnostic performance of strain ratio and shear wave velocity was evaluated by sensitivity and specificity at the optimum cutoff point and the area under the receiver operating characteristic curve.
Cases showed statistically significant higher median strain ratio of parotid and submandibular gland than control group (-value = 0.001). Total cases showed statistically significant higher median scores than control group (-value < 0.001). At cut-off value of (1.13); diagnostic accuracy, sensitivity and specificity were 97.6, 95.2 and 100% respectively with AUROC 0.954 and confidence interval: 0.840-0.995. Cases showed statistically significant higher median shear wave velocity of parotid gland than control group (-value = 0.022), with no statistically significant difference in submandibular gland in the two groups (-value = 0.216). Total cases showed statistically significant higher median scores than control group (-value < 0.001). At cut-off value of (23.5), diagnostic accuracy was 78.6% with a sensitivity of 81% and specificity of 76.2% with 0.819 AUROC and onfidence interval :0.669-0.920.
Our initial experience suggests that elastography may be potentially useful for diagnosis of chronic inflammatory conditions of the major salivary glands. This conclusion needs to be further validated large sample studies.
本研究旨在通过超声弹性成像评估大唾液腺的慢性炎症状态。
本研究纳入 21 例大唾液腺慢性炎症患者和 21 例健康成年志愿者。所有参与者均接受了 B 超和超声弹性成像检查。通过最佳截断点的灵敏度和特异性以及受试者工作特征曲线下的面积来评估应变比和剪切波速度的诊断性能。
病例组的腮腺和颌下腺的中位数应变比均明显高于对照组（-值=0.001）。病例组的总评分中位数明显高于对照组（-值<0.001）。在截断值为（1.13）时，诊断准确性、灵敏度和特异性分别为 97.6%、95.2%和 100%，AUROC 为 0.954，置信区间为 0.840-0.995。病例组的腮腺中位数剪切波速度明显高于对照组（-值=0.022），而两组的颌下腺无明显差异（-值=0.216）。病例组的总评分中位数明显高于对照组（-值<0.001）。在截断值为（23.5）时，诊断准确性为 78.6%，灵敏度为 81%，特异性为 76.2%，AUROC 为 0.819，置信区间为 0.669-0.920。
我们的初步经验表明，弹性成像可能对大唾液腺慢性炎症的诊断有一定的应用价值。这一结论需要进一步通过大样本研究来验证。
