Potenza D P, el-Mallakh R S
Conn Med. 1989 Jul;53(7):395-400.
Since the introduction of aspartame into the American food supply in 1981, it has grown to become the most widely used and accepted artificial sweetener. However, recent published and unpublished reports of headaches, seizures, blindness, and cognitive and behavioral changes with long-term, high-dose aspartame may be cause for concern. Physician awareness of the present clinical and research status of aspartame is important.
自1981年阿斯巴甜被引入美国食品供应以来，它已发展成为使用最广泛且被接受的人工甜味剂。然而，近期已发表和未发表的报告指出，长期高剂量摄入阿斯巴甜会引发头痛、癫痫、失明以及认知和行为改变，这可能令人担忧。医生了解阿斯巴甜目前的临床和研究状况很重要。
