Ojima Toshiyasu, Takifuji Katsunari, Nakamura Masaki, Nakamori Mikihito, Yamaue Hiroki
Second Department of Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan.
Surg Laparosc Endosc Percutan Tech. 2016 Feb;26(1):78-81. doi: 10.1097/SLE.0000000000000233.
The aim of this study was to compare the oncologic results of endoscopic submucosal dissection (ESD) for early gastric cancers (EGC) in remnant stomachs (RS) with results of ESD for EGC in normal stomachs (NS).
From 2002 to 2013, ESD was performed for 583 EGC lesions. ESD of the RS was performed for 34 lesions.
Two patients with EGC in the NS and 1 patient with EGC in the RS died from these gastric cancers. In all patients, the ESD treatments were considered outside of indications according to the pathologic results. The 5-year cause-specific survival rate was 99.5% for EGC patients with NS and 96.2% for EGC patients with RS. The 5-year overall survival rates were 88.4% for patients with NS and 58.4% for patients with RS.
On the basis of the favorable long-term oncologic outcomes, ESD for EGC in the RS can be considered feasible in clinical practice.
本研究旨在比较残胃(RS)早期胃癌(EGC)内镜黏膜下剥离术(ESD)与正常胃(NS)EGC的ESD肿瘤学结果。
2002年至2013年,对583例EGC病变进行了ESD。对34例病变进行了残胃ESD。
NS组2例EGC患者和RS组1例EGC患者死于这些胃癌。根据病理结果,所有患者的ESD治疗均被认为超出适应证范围。NS组EGC患者的5年病因特异性生存率为99.5%,RS组EGC患者为96.2%。NS组患者的5年总生存率为88.4%,RS组患者为58.4%。
基于良好的长期肿瘤学结果,残胃EGC的ESD在临床实践中可被认为是可行的。