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The 6-hydroxydopamine rotational model for the detection of dopamine agonist activity: reliability of effect from different locations of 6-hydroxydopamine.

作者信息

Costall B, Naylor R J, Pycock C

出版信息

J Pharm Pharmacol. 1975 Dec;27(12):943-6. doi: 10.1111/j.2042-7158.1975.tb10253.x.

DOI:10.1111/j.2042-7158.1975.tb10253.x
PMID:2668
Abstract
摘要

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The 6-hydroxydopamine rotational model for the detection of dopamine agonist activity: reliability of effect from different locations of 6-hydroxydopamine.用于检测多巴胺激动剂活性的6-羟基多巴胺旋转模型:6-羟基多巴胺不同给药部位效应的可靠性
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2
Phencyclidine-induced ipsilateral rotation in rats with unilateral 6-hydroxydopamine-induced lesions of the substantia nigra.苯环利定诱导的单侧6-羟基多巴胺致黑质损伤大鼠的同侧旋转
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Non-specific supersensitivity of striatal dopamine receptors after 6-hydroxydopamine lesion of the nigrostriatal pathway.黑质纹状体通路经6-羟基多巴胺损伤后纹状体多巴胺受体的非特异性超敏反应。
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Effects of chronic morphine treatment on dopamine-mediated turning behaviour in rats and mice with 6-hydroxydopamine-induced unilateral nigro-striatal lesions.慢性吗啡治疗对6-羟基多巴胺诱导的单侧黑质纹状体损伤大鼠和小鼠中多巴胺介导的旋转行为的影响。
Neuropharmacology. 1980 Mar;19(3):289-95. doi: 10.1016/0028-3908(80)90152-5.
5
Apomorphine and amphetamine stereotypy after 6-hydroxydopamine lesions of the substantia nigra.6-羟基多巴胺损毁黑质后的阿扑吗啡和苯丙胺刻板行为
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Behavioral correlates of dopaminergic supersensitivity.多巴胺能超敏反应的行为关联
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The role of forebrain dopamine systems in amphetamine induced stereotyped behavior in the rat.前脑多巴胺系统在苯丙胺诱发大鼠刻板行为中的作用。
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8
Antiparkinsonian drugs and dopaminergic neostriatal mechanisms: studies in rats with unilateral 6-hydroxydopamine (=6-OH-DA)-induced degeneration of the nigro-neostriatal DA pathway and quantitative recording of rotational behaviour.抗帕金森病药物与多巴胺能新纹状体机制:对单侧6-羟基多巴胺(=6-OH-DA)诱导黑质-新纹状体多巴胺能通路退变的大鼠的研究及旋转行为的定量记录
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Proceedings: Differences in circling responses following electrolytic and 6-hydroxydopamine lesions of the nigro-striatal pathway.论文集:黑质-纹状体通路电解损伤和6-羟基多巴胺损伤后转圈反应的差异
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6-hydroxydopamine-induced degeneration of the nigrostriatal dopamine pathway: the turning syndrome.6-羟基多巴胺诱导的黑质纹状体多巴胺能通路变性:旋转综合征
Pharmacol Ther B. 1976;2(1):37-40. doi: 10.1016/0306-039x(76)90016-7.

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Neurotox Res. 2007 Sep;12(2):125-34. doi: 10.1007/BF03033921.
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Neurotoxins and neurotoxic species implicated in neurodegeneration.与神经退行性变相关的神经毒素和神经毒性物质。
Neurotox Res. 2004;6(7-8):615-30. doi: 10.1007/BF03033456.
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Role of globus pallidus and substantia nigra efferent pathways in striatally evoked head turning in the rat.苍白球和黑质传出通路在大鼠纹状体诱发的头部转动中的作用。
Exp Brain Res. 1981;44(2):170-6. doi: 10.1007/BF00237338.
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Role of globus pallidus GABA and opiate receptors in apomorphine circling in nigro-striatal lesioned rats.苍白球γ-氨基丁酸和阿片受体在黑质-纹状体损伤大鼠阿扑吗啡旋转行为中的作用
Naunyn Schmiedebergs Arch Pharmacol. 1982 Apr;319(1):43-7. doi: 10.1007/BF00491477.
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Inhibitory effect of a selective kappa receptor agonist, U-50, 488H, on methamphetamine-elicited ipsilateral circling behavior in rats with unilateral nigral lesions.选择性κ受体激动剂U-50,488H对单侧黑质损伤大鼠甲基苯丙胺诱发的同侧转圈行为的抑制作用。
Psychopharmacology (Berl). 1989;97(2):219-21. doi: 10.1007/BF00442253.
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Differential effects of dopamine agonists upon stimulated limbic and striatal dopamine release: in vivo voltammetric data.多巴胺激动剂对刺激引起的边缘系统和纹状体多巴胺释放的不同作用:体内伏安法数据
Br J Pharmacol. 1991 Jan;102(1):45-50. doi: 10.1111/j.1476-5381.1991.tb12130.x.
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A comparative review of the pharmacology of nomifensine.诺米芬辛药理学的比较综述。
Br J Clin Pharmacol. 1977;4Suppl 2(Suppl 2):69S-75S. doi: 10.1111/j.1365-2125.1977.tb05762.x.
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Changes in dopamine receptor status after denervation or chronic receptor stimulation [proceedings].去神经支配或慢性受体刺激后多巴胺受体状态的变化[会议论文集]
Br J Pharmacol. 1979 Jul;66(3):492P-493P.
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Specificity of monoamine neurotoxins: rotational responses to dopaminergic agonists after unilateral 6-OHDA and 5,6-DHT lesions of the median forebrain bundle [proceedings].单胺神经毒素的特异性:中脑前束单侧6-羟基多巴胺和5,6-二羟基色胺损伤后对多巴胺能激动剂的旋转反应[会议论文集]
Br J Pharmacol. 1977 Mar;59(3):465P-466P.