脑转移瘤患者的脑症状与影响问卷：一项前瞻性长期随访研究
The Brain Symptom and Impact Questionnaire in brain metastases patients: a prospective long-term follow-up study.
作者信息
Pulenzas Natalie, Ray Saurabh, Zhang Liying, McDonald Rachel, Cella David, Rowbottom Leigha, Sahgal Arjun, Soliman Hany, Tsao May, Danjoux Cyril, Lechner Breanne, Chow Edward
机构信息
Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Oncology AbbVie, Abbott Park, IL, USA.
出版信息
CNS Oncol. 2016;5(1):31-40. doi: 10.2217/cns.15.41. Epub 2015 Dec 18.
AIMS
To assess the ability of the Brain Metastases Symptom and Impact Questionnaire (BASIQ) in evaluating symptoms and impact on daily life.
PATIENTS & METHODS: Patients with brain metastases completed BASIQ, Functional Assessment of Cancer Therapy-General, FACT-Brain at baseline and at 1, 2 and 3 months follow-ups.
RESULTS
Thirty-six patients completed all follow-ups. BASIQ correlated well (r ≥ 0.40) with FACT subscales, except for social/family and emotional wellbeing. Linear regression analysis found no significant changes in quality of life (QOL) over time in both the BASIQ and FACT scales. Therefore, the two questionnaires coincide as both detected nonchanges.
CONCLUSION
The ability of the BASIQ in evaluating symptoms and impact on over longer assessment periods was supported by the FACT questionnaires.
目的
评估脑转移症状与影响问卷（BASIQ）在评估症状及对日常生活影响方面的能力。
患者与方法
脑转移患者在基线时以及随访1、2和3个月时完成BASIQ、癌症治疗功能评估通用版（FACT - General）、FACT - 脑量表。
结果
36例患者完成了所有随访。BASIQ与FACT各子量表相关性良好（r≥0.40），社交/家庭及情感幸福感子量表除外。线性回归分析发现，BASIQ和FACT量表在生活质量（QOL）方面均未随时间出现显著变化。因此，两份问卷结果一致，均未发现变化。
结论
FACT问卷支持了BASIQ在更长评估期内评估症状及影响的能力。
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