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老年患者医院获得性肺炎的发病率及诊断

Hospital-acquired pneumonia incidence and diagnosis in older patients.

作者信息

Burton Louise A, Price Rosemary, Barr Karen E, McAuley Sean M, Allen Jennifer B, Clinton Aoibhinn M, Phillips Gabby, Marwick Charis A, McMurdo Marion E T, Witham Miles D

机构信息

Medical Research Institute, University of Dundee, Dundee, UK.

Department of Microbiology, NHS Tayside, Dundee, UK.

出版信息

Age Ageing. 2016 Jan;45(1):171-4. doi: 10.1093/ageing/afv168. Epub 2015 Dec 18.

Abstract

BACKGROUND

hospital-acquired pneumonia poses a hazard to older people who are hospitalised, yet few data exist on the incidence or risk factors in non-intensive care patients. This study aimed to determine the incidence of hospital-acquired pneumonia (HAP) in a sample of hospitalised older people.

METHODS

prospective survey of hospitalised older patients (>65 years) at a single centre over a 12-month period. Casenote and chart data were collected on acute medical, orthopaedic and Medicine for the Elderly wards. HAP was defined in accordance with the European and Scottish National Prevalence Survey 2011 definition. Key analyses were incidence of clinically suspected and case definition clinically confirmed HAP.

RESULTS

one thousand three hundred and two patients were included in the analysis. Five hundred and thirty-nine (41%) were male; mean age was 82 years (SD 8). Median length of hospital stay was 14 days (IQR 20). One hundred and fifty-seven episodes of HAP were clinically suspected in 143 patients (10.9% of admissions), but only 83 episodes in 76 patients met the diagnostic criteria (5.8% of admissions). The risk of HAP was 0.3% per day in hospital. Reasons for failure to meet the diagnostic criteria in 75 cases were lack of radiographic evidence in 60/75; lack of evidence of inflammation in 42/75, and lack of respiratory signs or symptoms in 13/75; 35/75 (47%) of cases lacked evidence in two or more domains.

CONCLUSION

HAP is common but over-diagnosed in older hospitalised patients.

摘要

背景

医院获得性肺炎对住院的老年人构成危害,但关于非重症监护患者的发病率或危险因素的数据很少。本研究旨在确定住院老年人样本中医院获得性肺炎(HAP)的发病率。

方法

对一个中心在12个月期间住院的老年患者(>65岁)进行前瞻性调查。收集了急性内科、骨科和老年医学病房的病历和图表数据。HAP根据2011年欧洲和苏格兰全国患病率调查的定义进行定义。主要分析是临床疑似HAP的发病率和病例定义临床确诊的HAP。

结果

1302名患者纳入分析。539名(41%)为男性;平均年龄82岁(标准差8)。住院中位时间为14天(四分位间距20)。143名患者(占入院患者的10.9%)临床疑似发生157次HAP发作,但只有76名患者的83次发作符合诊断标准(占入院患者的5.8%)。住院期间HAP的风险为每天0.3%。75例未达到诊断标准的原因中,60/75缺乏影像学证据;42/75缺乏炎症证据,13/75缺乏呼吸体征或症状;35/75(47%)的病例在两个或更多领域缺乏证据。

结论

HAP在住院老年患者中很常见,但存在过度诊断的情况。

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