Allen Rebecca H, Goldberg Alisa B
Women's and Infants' Hospital/Brown University, 101 Dudley Street, Providence, Rhode Island 02905-2401.
Harvard Medical School, Planned Parenthood League of Massachusetts, 1055 Commonwealth Ave., Boston, Massachusetts 02215-1001.
Contraception. 2016 Apr;93(4):277-291. doi: 10.1016/j.contraception.2015.12.001. Epub 2015 Dec 9.
First-trimester surgical abortion is a common, safe procedure with a major complication rate of less than 1%. Cervical dilation before suction abortion is usually accomplished using tapered mechanical dilators. Risk factors for major complications in the first trimester include increasing gestational age and provider inexperience. Cervical priming before first-trimester surgical abortion has been studied using osmotic dilators and pharmacologic agents, most commonly misoprostol. Extensive data demonstrate that a variety of agents are safe and effective at causing preoperative cervical softening and dilation; however, given the small absolute risk of complications, the benefit of routine use of misoprostol or osmotic dilators in first-trimester surgical abortion is unclear. Although cervical priming results in reduced abortion time and improved provider ease, it requires a delay of at least 1 to 3 h and may confer side effects. The Society of Family Planning does not recommend routine cervical priming for first-trimester suction abortion but recommends limiting consideration of cervical priming for women at increased risk of complications from cervical dilation, including those late in the first trimester, adolescents and women in whom cervical dilation is expected to be challenging.
孕早期手术流产是一种常见且安全的手术,主要并发症发生率低于1%。负压吸引流产术前的宫颈扩张通常使用锥形机械扩张器完成。孕早期主要并发症的风险因素包括孕周增加和术者经验不足。已使用渗透扩张器和药物制剂(最常用米索前列醇)对孕早期手术流产前的宫颈预处理进行了研究。大量数据表明,多种药物在引起术前宫颈软化和扩张方面是安全有效的;然而,鉴于并发症的绝对风险较小,孕早期手术流产常规使用米索前列醇或渗透扩张器的益处尚不清楚。尽管宫颈预处理可缩短流产时间并提高术者操作的便利性,但它需要至少延迟1至3小时,且可能带来副作用。计划生育协会不建议对孕早期负压吸引流产进行常规宫颈预处理,但建议对于宫颈扩张并发症风险增加的女性,包括孕早期晚期、青少年以及预计宫颈扩张有困难的女性,限制考虑宫颈预处理。