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简短干预对大量饮酒有效吗?两种文化背景下急诊科患者的比较。

Does Brief Intervention Work For Heavy Episodic Drinking? A Comparison of Emergency Department Patients in Two Cultures.

作者信息

Cherpitel Cheryl J, Ye Yu, Moskalewicz Jacek, Swiatkiewicz Grazyna

机构信息

Alcohol Research Group, 6475 Christie Avenue, Suite 400, Emeryville, CA, USA, 510 597-3453.

Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, POLAND.

出版信息

Alkohol Narkom. 2015 Sep;28(3):145-162. doi: 10.1016/j.alkona.2015.05.001. Epub 2015 Nov 10.

Abstract

Little has been reported on the efficacy of brief intervention (BI) among heavy episodic drinkers, although this drinking style is known to be especially harmful in relation to negative consequences including alcohol-related injuries. The comparative efficacy of BI is analyzed in two similar randomized controlled clinical trials of emergency department (ED) patients in two different cultures, both of which exhibit similar drinking styles of heavy episodic drinking: Poland and Mexican-Americans in the U.S. Improvements in drinking and problem outcomes are analyzed at 3-month and 12-month follow-up, using random effects modeling, among 446 Polish patients and 698 Mexican-American patients, randomized to screened only, assessment, and intervention conditions in each study. In Poland significant improvement was observed in all outcome measures for the assessed condition at 3-months compared to baseline, but only in the two problem variables at 12-months, while for the intervention condition, significant improvement was found in all outcome measures at both time periods; however, estimates of the interaction terms were not statistically significant. In the Mexica-American study, while significant improvement in nearly all outcome measures were observed at 3 months and 12 months for both conditions, estimates of the interaction terms suggest that for all drinking variables, but not problem variables, outcomes were significantly improved for the intervention condition over the assessed condition at 12 months, suggesting a 12-month intervention effect. Findings here are non-conclusive regarding a treatment effect of BI for heavy episodic drinking in ED patients. Given the mixed findings for BI in other ED studies, future studies need to explore the efficacy of BI in other populations and cultures exhibiting different drinking patterns to help identify what type of drinker would most benefit from BI in the ED setting.

摘要

尽管大量饮酒这种饮酒方式已知会对包括酒精相关伤害在内的负面后果特别有害,但关于简短干预(BI)对大量饮酒者的疗效报道甚少。在两项针对两种不同文化背景的急诊科(ED)患者的类似随机对照临床试验中,分析了BI的相对疗效,这两种文化背景的人群都表现出类似的大量饮酒的饮酒方式:波兰和美国的墨西哥裔美国人。在446名波兰患者和698名墨西哥裔美国患者中,采用随机效应模型,在3个月和12个月的随访中分析饮酒和问题结局的改善情况,这些患者在每项研究中被随机分配到仅筛查、评估和干预组。在波兰,与基线相比,评估组在3个月时所有结局指标均有显著改善,但在12个月时仅在两个问题变量上有改善,而干预组在两个时间段的所有结局指标上均有显著改善;然而,交互项的估计无统计学意义。在墨西哥裔美国人的研究中,虽然两组在3个月和12个月时几乎所有结局指标都有显著改善,但交互项的估计表明,对于所有饮酒变量而非问题变量,干预组在12个月时的结局相对于评估组有显著改善,提示有12个月的干预效果。关于BI对急诊科大量饮酒患者的治疗效果,此处的研究结果尚无定论。鉴于其他急诊科研究中BI的结果不一,未来的研究需要探索BI在其他具有不同饮酒模式的人群和文化中的疗效,以帮助确定哪种类型的饮酒者在急诊科环境中最能从BI中获益。

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