Cherpitel Cheryl J, Ye Yu, Bond Jason, Woolard Robert, Villalobos Susana, Bernstein Judith, Bernstein Edward, Ramos Rebeca
Public Health Institute, Alcohol Research Group, 6475 Christie Avenue, Suite 400, Emeryville, CA 94608, USA
Public Health Institute, Alcohol Research Group, 6475 Christie Avenue, Suite 400, Emeryville, CA 94608, USA.
Alcohol Alcohol. 2016 Mar;51(2):154-63. doi: 10.1093/alcalc/agv084. Epub 2015 Aug 4.
A randomized controlled trial of brief intervention (BI), for drinking and related problems, using peer health promotion advocates (promotores), was conducted among at-risk and alcohol-dependent Mexican-origin young adult emergency department (ED) patients, aged 18-30.
Six hundred and ninety-eight patients were randomized to: screened only (n = 78), assessed (n = 310) and intervention (n = 310). Primary outcomes were at-risk drinking and Rapid Alcohol Problems Screen (RAPS4) scores. Secondary outcomes were drinking days per week, drinks per drinking day, maximum drinks in a day and negative consequences of drinking.
At 3- and 12-month follow-up the intervention condition showed significantly lower values or trends on all outcome variables compared to the assessed condition, with the exception of the RAPS4 score; e.g. at-risk drinking days dropped from 2.9 to 1.7 at 3 months for the assessed condition and from 3.2 to 1.2 for the intervention condition. Using random effects modeling controlling for demographics and baseline values, the intervention condition showed significantly greater improvement in all consumption measures at 12 months, but not in the RAPS4 or negative consequences of drinking. Improvements in outcomes were significantly more evident for non-injured patients, those reporting drinking prior to the event, and those lower on risk taking disposition.
At 12-month follow-up this study demonstrated significantly improved drinking outcomes for Mexican-origin young adults in the ED who received a BI delivered by promotores compared to those who did not.
ClinicalTrials.gov.
NCT02056535.
在年龄为18 - 30岁、有风险及酒精依赖的墨西哥裔年轻成人急诊科患者中,开展了一项使用同伴健康促进倡导者(推广者)进行饮酒及相关问题简短干预(BI)的随机对照试验。
698名患者被随机分为:仅筛查组(n = 78)、评估组(n = 310)和干预组(n = 310)。主要结局为有风险饮酒和快速酒精问题筛查(RAPS4)得分。次要结局为每周饮酒天数、每次饮酒日饮酒量、一天中最大饮酒量以及饮酒的负面后果。
在3个月和12个月随访时,与评估组相比,干预组在所有结局变量上显示出显著更低的值或趋势,但RAPS4得分除外;例如,评估组在3个月时,有风险饮酒天数从2.9降至1.7,干预组从3.2降至1.2。使用控制人口统计学和基线值的随机效应模型,干预组在12个月时所有饮酒量指标上显示出显著更大的改善,但在RAPS4或饮酒负面后果方面没有。对于未受伤患者、报告在事件发生前饮酒的患者以及冒险倾向较低的患者,结局改善更为明显。
在12个月随访时,本研究表明,与未接受推广者进行的简短干预的急诊科墨西哥裔年轻成人相比,接受该干预的患者饮酒结局有显著改善。
ClinicalTrials.gov。
NCT02056535。