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使用李克特量表法降低前列腺癌放疗中的锥形束CT剂量

Cone beam CT dose reduction in prostate radiotherapy using Likert scale methods.

作者信息

Langmack Keith A, Newton Louise A, Jordan Suzanne, Smith Ruth

机构信息

1 Departments of Medical Physics, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham.

2 Departments of Radiotherapy, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham.

出版信息

Br J Radiol. 2016;89(1059):20150460. doi: 10.1259/bjr.20150460. Epub 2015 Dec 21.

Abstract

OBJECTIVE

To use a Likert scale method to optimize image quality (IQ) for cone beam CT (CBCT) soft-tissue matching for image-guided radiotherapy of the prostate.

METHODS

23 males with local/locally advanced prostate cancer had the CBCT IQ assessed using a 4-point Likert scale (4 = excellent, no artefacts; 3 = good, few artefacts; 2 = poor, just able to match; 1 = unsatisfactory, not able to match) at three levels of exposure. The lateral separations of the subjects were also measured. The Friedman test and Wilcoxon signed-rank tests were used to determine if the IQ was associated with the exposure level. We used the point-biserial correlation and a χ(2) test to investigate the relationship between the separation and IQ.

RESULTS

The Friedman test showed that the IQ was related to exposure (p = 2 × 10(-7)) and the Wilcoxon signed-rank test demonstrated that the IQ decreased as exposure decreased (all p-values <0.005). We did not find a correlation between the IQ and the separation (correlation coefficient 0.045), but for separations <35 cm, it was possible to use the lowest exposure parameters studied.

CONCLUSION

We can reduce exposure factors to 80% of those supplied with the system without hindering the matching process for all patients. For patients with lateral separations <35 cm, the exposure factors can be reduced further to 64% of the original values.

ADVANCES IN KNOWLEDGE

Likert scales are a useful tool for measuring IQ in the optimization of CBCT IQ for soft-tissue matching in radiotherapy image guidance applications.

摘要

目的

采用李克特量表法优化锥形束CT(CBCT)软组织匹配的图像质量(IQ),用于前列腺癌的图像引导放射治疗。

方法

23例局部/局部晚期前列腺癌男性患者在三个曝光水平下,使用4点李克特量表(4 = 优秀,无伪影;3 = 良好,少量伪影;2 = 差,勉强能匹配;1 = 不满意,无法匹配)评估CBCT的IQ。还测量了受试者的横向间距。采用弗里德曼检验和威尔科克森符号秩检验来确定IQ是否与曝光水平相关。我们使用点二列相关和χ²检验来研究间距与IQ之间的关系。

结果

弗里德曼检验表明IQ与曝光有关(p = 2×10⁻⁷),威尔科克森符号秩检验表明IQ随曝光降低而降低(所有p值<0.005)。我们未发现IQ与间距之间存在相关性(相关系数0.045),但对于间距<35 cm的情况,可以使用所研究的最低曝光参数。

结论

我们可以将曝光因素降低至系统提供值的80%,而不会妨碍所有患者的匹配过程。对于横向间距<35 cm的患者,曝光因素可进一步降低至原始值的64%。

知识进展

在放射治疗图像引导应用中,李克特量表是优化CBCT软组织匹配IQ时测量IQ的有用工具。

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