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锥形束 CT 成像:一种优化和评估同期成像剂量的简便方法,基于患者特定的衰减,用于骨盆放疗。

CBCT imaging: a simple approach for optimising and evaluating concomitant imaging doses, based on patient-specific attenuation, during radiotherapy pelvis treatment.

机构信息

Radiotherapy Physics, St Bartholomew's Hospital, London, UK.

North West Anglia NHS Foundation Trust, England, UK.

出版信息

Br J Radiol. 2021 Aug 1;94(1124):20210068. doi: 10.1259/bjr.20210068.

Abstract

OBJECTIVES

A simple, robust method, for optimising cone-beam CT (CBCT) dose and image quality for pelvis treatment, based on patient-specific attenuation.

METHODS

Methods were investigated for grouping patients into four imaging categories (small [S], medium [M], large [L], extra large [XL]), based on planning-CT CTDIvol, and phantoms constructed to represent each group. CBCTs with varying kV, mA and ms honed in on the best settings, with a bladder noise of 25 HU. A patient pilot study clinically verified the new imaging settings.

RESULTS

The planning CTDIvol is a reliable method for grouping patients. Phantom measurements from the S, M and L groups show doses significantly reduced (19-83% reduction), whilst the XL group required an increase of 39%. Phantom TLD measurements showed the number of scans needed to increase rectal organ at risk (OAR) dose by 1 Gy was 143 (S group) and 50 (M group). Images were qualitatively assessed as sufficient by clinicians.

CONCLUSION

Patient-specific CBCT modes are in use clinically with dose reductions across all modes except Pelvis XL, keeping doses ALARP and images optimal. Consideration of OAR doses controls the number of CBCTs allowed to ensure adherence to OAR tolerance. Reporting CBCT doses in "scans per Gray" allows clinicians to make informed decisions regarding the imaging schedule and concomitant doses.

ADVANCES IN KNOWLEDGE

Patient grouping at planning CT, using CTDIvol, allows for CBCT imaging protocols to be selected based on patient specific attenuation. Reporting OAR doses in terms of "scans per Gray" allows translation of imaging dose risk to the Oncologist.

摘要

目的

基于患者特定衰减,开发一种简单、稳健的方法,优化骨盆治疗用锥形束 CT(CBCT)的剂量和图像质量。

方法

根据计划 CT 的 CTDIvol 对患者进行分组,将患者分为四个成像类别(小[S]、中[M]、大[L]、特大[XL]),并构建代表每个组的体模。对体模进行了不同千伏(kV)、毫安(mA)和毫秒(ms)的 CBCT 优化,以获得最佳设置,同时膀胱噪声为 25 HU。一项患者试点研究对新的成像设置进行了临床验证。

结果

计划 CTDIvol 是一种可靠的分组方法。来自 S、M 和 L 组的体模测量结果显示剂量显著降低(降低 19-83%),而 XL 组需要增加 39%。体模 TLD 测量结果显示,为将直肠危及器官(OAR)剂量增加 1 Gy 所需的扫描次数为 143(S 组)和 50(M 组)。临床医生对图像质量评估为足够。

结论

基于患者的 CBCT 模式已在临床中使用,除了骨盆 XL 外,所有模式的剂量都有所降低,使剂量保持在合理可行尽量低(ALARP)并保持图像质量最佳。OAR 剂量的考虑控制允许的 CBCT 数量,以确保符合 OAR 耐受度。以“每 Gray 扫描次数”报告 CBCT 剂量可使临床医生能够就成像计划和伴随剂量做出明智的决策。

知识进展

在计划 CT 时使用 CTDIvol 对患者进行分组,允许根据患者的特定衰减选择 CBCT 成像协议。以“每 Gray 扫描次数”报告 OAR 剂量可将成像剂量风险转化为肿瘤学家的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7909/8523193/bb23b8f351e4/bjr.20210068.g002.jpg

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