Khan Muhammad Babar, Bashir Muhammad Umair, Kumar Rajesh, Enam Syed Ather
Department of Surgery, Section of Neurosurgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan.
J Craniovertebr Junction Spine. 2015 Oct-Dec;6(4):195-9. doi: 10.4103/0974-8237.167881.
Our present study aims to assess the short and long-term postoperative outcome of microscopic interlaminar decompression from a neurosurgical center in a developing country and also aims to further determine any predictors of functional outcome.
All patients with moderate to severe symptomatic stenosis undergoing elective posterior lumbar spinal decompression were prospectively enrolled in a database. Preoperative, 2 weeks and 2 years postoperative Oswestry Disability Index (ODI) scores were determined for all patients. These scores were retrospectively compared using repeated measures analysis of variance. Further, linear regression modelling was applied to determine the effect of preoperative ODI, body mass index, age, prior physiotherapy, duration of symptoms, and single or multiple level decompression on the change in ODI at 2 weeks and 2 years follow-up respectively.
A total of 60 consecutive patients (40 males, 20 females) were included for statistical analysis. The percentage of patients with a minimum clinically important difference (MCID), using an ODI threshold value of 10, was 86.7% (n = 52) at the 2 weeks postoperative follow-up. At the 2 years follow-up assessment, 3.3% (n = 2) patients who had earlier not achieved MCID did so, 78.3% (n = 47) of patients were found to have a change in ODI score of <10 or no change, while 18.3% (n = 11) reported a deterioration in their ODI scores. The preoperative ODI score was an independent predictor of change in ODI score at 2 weeks and 2 years respectively (P < 0.0005). The duration of symptoms prior to surgery was found to predict the change in ODI at 2 years follow-up (P = 0.04).
The evidence regarding the long-term and short-term efficacy of microscopic interlaminar decompression in symptomatic lumbar stenosis is overwhelming. Preoperative ODI scores and duration of symptoms prior to surgery can predict postoperative outcomes.
我们目前的研究旨在评估来自一个发展中国家神经外科中心的显微镜下椎板间减压术的短期和长期术后结果,并进一步确定功能结果的任何预测因素。
所有接受择期后路腰椎减压术的中度至重度症状性狭窄患者均被前瞻性纳入数据库。为所有患者确定术前、术后2周和2年的奥斯威斯功能障碍指数(ODI)评分。使用重复测量方差分析对这些评分进行回顾性比较。此外,应用线性回归模型分别确定术前ODI、体重指数、年龄、先前的物理治疗、症状持续时间以及单节段或多节段减压对术后2周和2年随访时ODI变化的影响。
共有60例连续患者(40例男性,20例女性)纳入统计分析。术后2周随访时,使用ODI阈值10,达到最小临床重要差异(MCID)的患者百分比为86.7%(n = 52)。在2年随访评估中,早期未达到MCID的患者中有3.3%(n = 2)达到了,78.3%(n = 47)的患者ODI评分变化<10或无变化,而18.3%(n = 11)报告其ODI评分恶化。术前ODI评分分别是术后2周和2年时ODI评分变化的独立预测因素(P < 0.0005)。术前症状持续时间被发现可预测术后2年随访时的ODI变化(P = 0.04)。
关于显微镜下椎板间减压术治疗症状性腰椎管狭窄的长期和短期疗效的证据确凿。术前ODI评分和术前症状持续时间可预测术后结果。