Lord Rachel N, George Keith, Jones Helen, Somauroo John, Oxborough David
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University , Tom Reilly Building, Byrom Street, Liverpool, L3 3AF , UK.
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University , Tom Reilly Building, Byrom Street, Liverpool, L3 3AF , UK ; Countess of Chester Hospital, NHS Trust , Chester , UK.
Echo Res Pract. 2014 Sep 1;1(1):31-41. doi: 10.1530/ERP-14-0011. Epub 2014 Jul 28.
This study aimed to establish feasibility for myocardial speckle tracking (MST) and intra-observer reliability of both MST and tissue velocity imaging (TVI)-derived right ventricular (RV) strain (ϵ) and strain rate (SR) at rest and during upright incremental exercise. RV ϵ and SR were derived using both techniques in 19 healthy male participants. MST-derived ϵ and SR were feasible at rest (85% of segments tracked appropriately). Feasibility reduced significantly with progressive exercise intensity (3% of segments tracking appropriately at 90% maximum heart rate (HRmax)). Coefficient of variations (CoVs) of global ϵ values at rest was acceptable for both TVI and MST (7-12%), with low bias and narrow limits of agreement. Global SR data were less reliable for MST compared with TVI as demonstrated with CoV data (systolic SR=15 and 61%, early diastolic SR=16 and 17% and late diastolic SR=26 and 31% respectively). CoVs of global RV ϵ and SR obtained at 50% HRmax were acceptable using both techniques. As exercise intensity increased to 70 and 90% HRmax, reliability of ϵ and SR values reduced with larger variability in MST. We conclude that RV global and regional ϵ and SR data are feasible, comparable and reliable at rest and at 50% HRmax using both MST and TVI. Reliability was reduced during higher exercise intensities with only TVI acceptable for clinical and scientific use.
本研究旨在确定心肌斑点追踪（MST）的可行性，以及MST和组织速度成像（TVI）得出的静息及直立递增运动期间右心室（RV）应变（ϵ）和应变率（SR）的观察者内可靠性。在19名健康男性参与者中使用这两种技术得出RV ϵ和SR。MST得出的ϵ和SR在静息时是可行的（85%的节段追踪合适）。随着运动强度增加，可行性显著降低（在最大心率（HRmax）的90%时，3%的节段追踪合适）。静息时TVI和MST的整体ϵ值变异系数（CoV）均可接受（7 - 12%），偏差低且一致性界限窄。与TVI相比，MST的整体SR数据可靠性较低，CoV数据表明（收缩期SR分别为15%和61%，舒张早期SR分别为16%和17%，舒张晚期SR分别为26%和31%）。使用这两种技术在HRmax的50%时获得的整体RV ϵ和SR的CoV均可接受。随着运动强度增加到HRmax的70%和90%，ϵ和SR值的可靠性降低，MST中的变异性更大。我们得出结论，使用MST和TVI，RV整体和局部的ϵ和SR数据在静息和HRmax的50%时是可行、可比且可靠的。在更高运动强度期间可靠性降低，只有TVI可用于临床和科研。
