Walker R J, Tiller D J, Horvath J S, Duggin G G
Department of Renal Medicine, Royal Prince Alfred Hospital, NSW, Australia.
Aust N Z J Med. 1989 Apr;19(2):154-5. doi: 10.1111/j.1445-5994.1989.tb00231.x.
Cyclosporin A has been associated with an apparent increased incidence of non Hodgkins lymphoma, most often in conjunction with multiple immunosuppressive agents. We report a patient who developed a non Hodgkins lymphoma arising in the right tonsillar fossa six months following renal transplantation. The development of the lymphoma was associated with seroconversion for the Epstein Barr capsid antigen and nuclear antigen. The patient was receiving cyclosporin A alone as immunosuppression.
环孢素A与非霍奇金淋巴瘤的发病率明显增加有关，最常见于与多种免疫抑制剂联合使用时。我们报告一名肾移植后六个月在右侧扁桃体窝发生非霍奇金淋巴瘤的患者。淋巴瘤的发生与EB病毒衣壳抗原和核抗原的血清学转换有关。该患者仅接受环孢素A作为免疫抑制剂。
