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[Regression of cerebral post-transplantation lymphoma under cyclosporin A reduction].

作者信息

Fric M, Hartmann A, Klehr H U, Pfeifer U, Herberhold C

机构信息

Neurologische Universitätsklinik, Universität Bonn.

出版信息

Klin Wochenschr. 1990 Dec 4;68(23):1189-94. doi: 10.1007/BF01815278.

DOI:10.1007/BF01815278
PMID:2280583
Abstract

4.5 months after successful kidney transplantation a Non-Hodgkin-lymphoma with polymorph centroblastic appearance of the tonsillar gland developed in a 21 years old male patient during immunosuppressive therapy with cyclosporine A and prednisone parallel to infection with Epstein Barr virus. Focal epileptic seizures occurred and were due to cerebral posttransplantation lymphomas as proven by brain biopsy. Reduction of immunosuppressive therapy led to complete remission as shown by CCT and MRI.

摘要

相似文献

1
[Regression of cerebral post-transplantation lymphoma under cyclosporin A reduction].
Klin Wochenschr. 1990 Dec 4;68(23):1189-94. doi: 10.1007/BF01815278.
2
Malignant lymphoma in a renal transplant patient on cyclosporin A therapy.一名接受环孢素A治疗的肾移植患者发生恶性淋巴瘤。
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Spontaneous regression of a small non-cleaved cell malignant lymphoma (non-Burkitt's lymphoblastic lymphoma). Morphologic, immunohistological, and immunoglobulin gene analysis.一例小无裂细胞恶性淋巴瘤(非伯基特淋巴母细胞淋巴瘤)的自发消退。形态学、免疫组织化学及免疫球蛋白基因分析。
Cancer. 1988 Aug 15;62(4):791-4. doi: 10.1002/1097-0142(19880815)62:4<791::aid-cncr2820620425>3.0.co;2-m.
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Primary reticulum cell sarcoma of the brain in a renal transplantation recipient.一名肾移植受者发生的原发性脑网状细胞肉瘤。
J Neurosurg. 1974 Aug;41(2):235-9. doi: 10.3171/jns.1974.41.2.0235.
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Non-Hodgkin lymphoma of brain occurring after cardiac transplantation.
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Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy.肾同种移植及硫唑嘌呤和泼尼松治疗后发生的网状细胞肉瘤
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Primary cerebral lymphoma with spontaneous remission.原发性中枢神经系统淋巴瘤伴自发缓解。
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引用本文的文献

1
An instructive false diagnosis: steroid-induced complete remission of a CNS tumor--probably lymphoma.一个具有指导意义的误诊:类固醇诱导的中枢神经系统肿瘤(可能为淋巴瘤)完全缓解。
Neurosurg Rev. 1998;21(1):48-51. doi: 10.1007/BF01111485.

本文引用的文献

1
Polymorphic diffuse B-cell hyperplasias and lymphomas in renal transplant recipients.肾移植受者中的多形性弥漫性B细胞增生和淋巴瘤。
Cancer Res. 1981 Nov;41(11 Pt 1):4262-79.
2
Skin cancer in Caucasian renal allograft recipients living in a subtropical climate.生活在亚热带气候地区的白种人肾移植受者中的皮肤癌
Surgery. 1980 Feb;87(2):177-83.
3
Epstein-Barr virus (EBV) induced polyclonal and monoclonal B-cell lymphoproliferative diseases occurring after renal transplantation. Clinical, pathologic, and virologic findings and implications for therapy.
肾移植后发生的爱泼斯坦-巴尔病毒(EBV)诱导的多克隆和单克隆B细胞淋巴增殖性疾病。临床、病理和病毒学发现及治疗意义。
Ann Surg. 1983 Sep;198(3):356-69. doi: 10.1097/00000658-198309000-00012.
4
Summary: symposium on Epstein-Barr virus-induced lymphoproliferative diseases in immunodeficient patients.总结:免疫缺陷患者中爱泼斯坦-巴尔病毒诱导的淋巴增殖性疾病研讨会
Cancer Res. 1981 Nov;41(11 Pt 1):4302-4.
5
Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy.在环孢素-类固醇治疗下发生的淋巴瘤和淋巴增殖性病变的可逆性。
Lancet. 1984 Mar 17;1(8377):583-7. doi: 10.1016/s0140-6736(84)90994-2.
6
Malignant lymphomas in transplantation patients.移植患者中的恶性淋巴瘤。
Transplant Proc. 1969 Mar;1(1):106-12.
7
Immunosuppression and malignant neoplasms.免疫抑制与恶性肿瘤
N Engl J Med. 1970 Oct 22;283(17):934-5.
8
Immunosuppression and malignant neoplasms.
N Engl J Med. 1970 Oct 22;283(17):934. doi: 10.1056/NEJM197010222831714.
9
Primary malignancy in patients undergoing immunosuppression for renal transplantation.
Transplantation. 1969 Aug;8(2):209-12. doi: 10.1097/00007890-196908000-00033.
10
Iatrogenic alterations of immunologic surveillance in man and their influence on malignancy.人类免疫监视的医源性改变及其对恶性肿瘤的影响。
Transplant Rev. 1971;7:112-45. doi: 10.1111/j.1600-065x.1971.tb00465.x.