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精索静脉曲张:诊断难题、治疗挑战及未来展望

The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives.

作者信息

Chiba Koji, Ramasamy Ranjith, Lamb Dolores J, Lipshultz Larry I

机构信息

Center for Reproductive Medicine; Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.

出版信息

Asian J Androl. 2016 Mar-Apr;18(2):276-81. doi: 10.4103/1008-682X.167724.

Abstract

A varicocele is defined as the abnormal dilation of the internal testicular vein and pampiniform venus plexus within the spermatic cord. If a semen analysis is not obtained from the adolescent male, in the absence of other symptoms, the main clinical indication used by many urologists to recommend repair is testicular atrophy. The varicocele may result in testicular damage in some males causing testicular atrophy with impaired sperm production and decreased Leydig cell function, while in other males the varicocele may seemingly cause no ill effects. In adult men, varicoceles are frequently present and surgically correctable, yet the measurable benefits of surgical repair are slight according to a Cochrane review. While occurring more commonly in infertile men than fertile men, only 20% of men with a documented varicocele will suffer from fertility problems. Most varicoceles found in adolescents are detected during a routine medical examination, and it is difficult to predict which adolescent presenting with a varicocele will ultimately show diminished testicular function in adolescence or adulthood. As in adults, the mainstay of treatment for varicocele in adolescents is surgical correction. However, unlike an adult varicocelectomy (the microsurgical approach is the most common), treatment for an adolescent varicocele is more often laparoscopic. Nevertheless, the goals of treatment are the same in the adolescent and adult patients. Controversy remains as to which patients to treat, when to initiate the treatment, and what type of treatment is the best. This review will present the current understanding of the etiology, diagnosis and treatment of the adolescent varicocele.

摘要

精索静脉曲张被定义为精索内睾丸静脉和蔓状静脉丛的异常扩张。如果未对青春期男性进行精液分析,且无其他症状,许多泌尿外科医生推荐修复手术的主要临床指征是睾丸萎缩。精索静脉曲张可能在一些男性中导致睾丸损伤,引起睾丸萎缩,精子生成受损以及睾丸间质细胞功能下降,而在其他男性中,精索静脉曲张似乎不会产生不良影响。在成年男性中,精索静脉曲张很常见且可通过手术矫正,但根据Cochrane综述,手术修复的可衡量益处很小。虽然精索静脉曲张在不育男性中比在可育男性中更常见,但有记录的精索静脉曲张患者中只有20%会出现生育问题。在青少年中发现的大多数精索静脉曲张是在常规体检中检测到的,很难预测哪些患有精索静脉曲张的青少年最终会在青春期或成年期出现睾丸功能减退。与成年人一样,青少年精索静脉曲张的主要治疗方法是手术矫正。然而,与成人精索静脉结扎术(显微手术方法最常见)不同,青少年精索静脉曲张的治疗更多采用腹腔镜手术。尽管如此,青少年和成年患者的治疗目标是相同的。关于哪些患者需要治疗、何时开始治疗以及哪种治疗方法最佳仍存在争议。本综述将介绍目前对青少年精索静脉曲张的病因、诊断和治疗的认识。

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