Moon Dong Chan, Kim Byung-Yong, Nam Hyang-Mi, Jang Geum-Chan, Jung Suk-Chan, Lee Hee-Soo, Park Yong-Ho, Lim Suk-Kyung
Bacterial Disease Division, Animal and Plant Quarantine Agency, Anyang 14089, Republic of Korea.
ChunLab Inc., Seoul National University, Seoul 08826, Republic of Korea.
J Microbiol Biotechnol. 2016 Apr 28;26(4):799-805. doi: 10.4014/jmb.1509.09015.
Methicillin-resistant Staphylococcus aureus (MRSA), the major causative agent of nosocomial infection, has also been reported from non-human sources. A sequence type (ST) 541 MRSA isolate designated K12PJN53 was isolated from a healthy pig in 2012. The genome of K12PJN53 consists of 44 contiguous sequences (contigs), totalling 2,880,108 bases with 32.88% GC content. Among the annotated contigs, 14, 17, and 18 contained genes related to antimicrobial resistance, adherence, and toxin genes, respectively. The genomic distance of strain K12PJN53 was close to the ST398 strains. This is the first report of the draft genome sequence of a novel livestock-associated MRSA ST541 strain.
耐甲氧西林金黄色葡萄球菌（MRSA）是医院感染的主要病原体，也有来自非人类源的报道。一株序列型（ST）541的MRSA分离株K12PJN53于2012年从一头健康猪中分离得到。K12PJN53的基因组由44个连续序列（重叠群）组成，共计2,880,108个碱基，GC含量为32.88%。在注释的重叠群中，分别有14个、17个和18个包含与抗菌抗性、黏附及毒素基因相关的基因。菌株K12PJN53的基因组距离与ST398菌株接近。这是新型家畜相关MRSA ST541菌株基因组草图序列的首次报道。
