Ueda Norichika, Arai Hiroki, Honda Masahito, Yoshida Kyotaro
The Department of Urology, Kinki Central Hospital of Mutual Aid Association of Public Teachers.
The Department of Pathology, Kinki Central Hospital of Mutual Aid Association of Public Teachers.
Hinyokika Kiyo. 2015 Nov;61(11):445-8.
An 83-year-old man presented with asymptomatic macroscopic hematuria while being treated for prostate cancer with hormonal therapy in January 2009. Cystoscopy revealed a 5 mm surface-smooth non pedunculated tumor lateral to the left ureteral orifice. Transurethral resection was carried out to examine the histology of the tumor. Histopathologic examination revealed the tumor arranged in a pseudoglandular pattern covered with erosive urothelial cells. The tumor had inconspicuous nucleoli, and abundant eosinophilic cytoplasm. An immunohistochemical study showed the tumor cells were positively stained for chromogranin A, synaptophysin, CD56, and NSE. Ki67 index of the tumor was below 2 %, indicating that the tumor was a carcinoid tumor. He showed no carcinoid syndrome, and neither recurrence nor metastasis has been detected for 66 months.
一名83岁男性在2009年1月接受前列腺癌激素治疗时出现无症状肉眼血尿。膀胱镜检查发现左输尿管口外侧有一个5毫米大小、表面光滑的无蒂肿瘤。进行了经尿道切除术以检查肿瘤的组织学。组织病理学检查显示肿瘤呈假腺管样排列，表面覆盖有糜烂的尿路上皮细胞。肿瘤核仁不明显，嗜酸性细胞质丰富。免疫组织化学研究显示肿瘤细胞嗜铬粒蛋白A、突触素、CD56和NSE呈阳性染色。肿瘤的Ki67指数低于2%，表明该肿瘤为类癌肿瘤。他没有类癌综合征，66个月来未检测到复发或转移。
