Israelsen Paul E, Sadda SriniVas R, Dorn Jessy D, Humayun Mark S, Olmos de Koo Lisa C
*Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California; †Department of Ophthalmology, Doheny Eye Institute, Los Angeles, California; and ‡Department of Ophthalmology, Second Sight Medical Products, Sylmar, California.
Retin Cases Brief Rep. 2016 Fall;10(4):382-5. doi: 10.1097/ICB.0000000000000269.
To explore the utility of using ultra-widefield imaging to visualize the Argus II implant in the eyes of three patients with retinitis pigmentosa.
Case series of three patients with retinitis pigmentosa who were implanted with the Argus II Retinal Prosthesis System; two of whom were enrolled in the Argus II clinical trial and one received the implant after the commercial release of the device. Optomap widefield fundus autofluorescence and color images of both eyes were taken in all three patients by an experienced technician using the Optos 200Tx imaging system. Analysis focused on fundus autofluorescence images of the implanted eyes and consisted of assessing the location and configuration of the Argus II electrode array and cable, and also the condition of the surrounding retina. Analysis was led by an experienced vitreoretinal surgeon.
Optos fundus autofluorescence images of the implanted eyes in all 3 patients gave a wide-angle view of the retina, with the electrode array and cable clearly visible. The status of the array and cable was able to be determined without difficulty. All 3 cases showed an appropriate mild-to-moderate bowing of the cable, and also the electrode array being positioned on or near the macula with a superotemporal tilt. Other features, such as "bone spicules," were also clearly seen. Optos color images were not as useful in the analysis because of an exaggerated green light artifact seen in the implanted versus the nonimplanted eyes.
Optomap fundus autofluorescence widefield images are useful in determining the configuration of the Argus II cable and the position of the electrode array on the retina and therefore are a useful component of the postoperative surveillance of patients implanted with the device. Using autofluorescence avoids the generation of a light reflection artifact often seen with Optos color imaging.
探讨使用超广角成像技术观察三名视网膜色素变性患者眼中阿格斯II型植入物的效用。
对三名植入阿格斯II型视网膜假体系统的视网膜色素变性患者进行病例系列研究；其中两名患者参加了阿格斯II型临床试验，一名患者在该设备商业发布后接受了植入。由一名经验丰富的技术人员使用Optos 200Tx成像系统为所有三名患者的双眼拍摄Optomap超广角眼底自发荧光和彩色图像。分析重点为植入眼的眼底自发荧光图像，包括评估阿格斯II型电极阵列和电缆的位置及形态，以及周围视网膜的状况。分析由一名经验丰富的玻璃体视网膜外科医生主导。
所有3名患者植入眼的Optos眼底自发荧光图像提供了视网膜的广角视图，电极阵列和电缆清晰可见。能够轻松确定阵列和电缆的状态。所有3例均显示电缆有适当的轻度至中度弯曲，电极阵列位于黄斑上或附近，并伴有颞上倾斜。其他特征，如“骨针”，也清晰可见。由于在植入眼与未植入眼中看到的绿光伪影夸大，Optos彩色图像在分析中不太有用。
Optomap眼底自发荧光广角图像有助于确定阿格斯II型电缆的形态以及电极阵列在视网膜上的位置，因此是植入该设备患者术后监测的有用组成部分。使用自发荧光可避免Optos彩色成像中常见的光反射伪影。
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