Shandong Provincial Research Center for Bioinformatic Engineering and Technique, School of Life Sciences, Shandong University of Technology, Zibo 255049, PR China.
Trends Pharmacol Sci. 2016 Mar;37(3):169-171. doi: 10.1016/j.tips.2015.11.010. Epub 2015 Dec 17.
An increasing number of studies show that alterations in intestinal microbiota are linked with metabolic diseases. Here, we propose that intestinal microbiota regulation by polyphenols may be an important mechanism underlying their therapeutic benefits for metabolic diseases. This helps elucidate the intriguing pharmacology of polyphenols and optimize the treatment of metabolic diseases.
越来越多的研究表明,肠道微生物群的改变与代谢性疾病有关。在这里,我们提出多酚对肠道微生物群的调节可能是其治疗代谢性疾病的重要机制。这有助于阐明多酚令人着迷的药理学,并优化代谢性疾病的治疗。