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GLYCINE SYNTHESIS AND METABOLISM IN ESCHERICHIA COLI.大肠杆菌中的甘氨酸合成与代谢
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Intermediatry metabolism of Diplococcus glycinophilus. I. Glycine cleavage and one-carbon interconversions.甘氨酸嗜双球菌的中间代谢。I. 甘氨酸裂解和一碳相互转化。
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Role of methionine in the regulation of the synthesis of serine hydroxymethyltransferase in Escherichia coli.甲硫氨酸在大肠杆菌中对丝氨酸羟甲基转移酶合成的调控作用。
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Regulation of synthesis of serine hydroxymethyltransferase in chemostat cultures of Escherichia coli.大肠杆菌恒化器培养物中丝氨酸羟甲基转移酶合成的调控
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Escherichia coli K12 mutants defective in the glycine cleavage enzyme system.在甘氨酸裂解酶系统中存在缺陷的大肠杆菌K12突变体。
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metR基因产物和同型半胱氨酸对大肠杆菌glyA基因的调控

Regulation of the Escherichia coli glyA gene by the metR gene product and homocysteine.

作者信息

Plamann M D, Stauffer G V

机构信息

Department of Microbiology, University of Iowa, Iowa City 52242.

出版信息

J Bacteriol. 1989 Sep;171(9):4958-62. doi: 10.1128/jb.171.9.4958-4962.1989.

DOI:10.1128/jb.171.9.4958-4962.1989
PMID:2670901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC210303/
Abstract

The methionine component of glyA gene regulation in Escherichia coli K-12 was investigated. The results indicate that the glyA gene is positively controlled by the metR gene product. Activation of glyA by the MetR protein requires homocysteine, an intermediate in methionine biosynthesis. The positive-acting metR regulatory system functions independently of a regulatory system shown previously to control glyA gene expression.

摘要

对大肠杆菌K-12中glyA基因调控的甲硫氨酸成分进行了研究。结果表明，glyA基因受metR基因产物的正向调控。MetR蛋白对glyA的激活需要同型半胱氨酸，它是甲硫氨酸生物合成的中间产物。起正向作用的metR调控系统独立于先前显示的控制glyA基因表达的调控系统发挥作用。