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非洲原住民的唇裂、牙槽突裂和腭裂:人口统计学与治疗结果的最新情况

CLEFT LIP, ALVEOLUS AND PALATE IN AFRICAN NATIVES: AN UPDATE ON DEMOGRAPHICS AND MANAGEMENT OUTCOME.

作者信息

Akintububo O B, Ojo E O, Kokong D D, Adamu S A, Nnadozie U U, Yunusa-Kaltungo Z, Jalo I, Dauda A M

机构信息

Oral and Maxillofacial Dept, FEDERAL MEDICAL CENTRE, GOMBE.

General Surgery Unit of Surgery Dept, FEDERAL MEDICAL CENTRE, GOMBE.

出版信息

Afr J Med Med Sci. 2014 Sep;43(Suppl 1):141-146.

Abstract

BACKGROUND

Development of craniofacial structures is a complex process and disruption of any of the numerous steps can lead to development of oro-facial clefts. This is a surgically amenable anomaly as from early life that has had conflicting pattern of demographics reported by various researchers globally. There are several factors that are critical to the surgical outcome.

OBJECTIVE

Study the demographics and the management outcome of cleft lip, alveolus and palate and highlight factors responsible for improved care in recent time.

DESIGN

Descriptive cohort study.

SETTING

Tertiary health institution.

METHOD

All consecutive patients managed for cleft lip, alveolus and palate (CLAP) over 7years and 10months were studied.

OUTCOME

Cleft lip, alveolus and palate repair was performed on 149 patients, January 1, 2001- December 31, 2008 with an incidence of 2.1/1000 live births. From this, 27 patients, averaging 4.5 patients per year were operated for the first 6 1/3 years while the remaining 122(81.9%) the next 1 1/2 years, averaging 81.6 patients yearly. Their ages ranged from 3 months - 60 years with 77 (51.7%) males and 72 (48.3.0%) females. Cleft lip was the main presentation in 108(72.5%) of which 72(66.7%) were left sided. Bilateral cleft lip were14 (9.4%). Five (3.4%) patients had associated anomalies out of which 3(60.0%) had CLAP while 2(40.0%) isolated cleft lip or palate. The technique for cleft lip repair was Millard's and Noordhoof's while palatal cleft was the two-flap palatoplasty with intravelar veloplasty. Success was recorded in 142(95.3%) with complication observed in 7(4.7%) patients.

CONCLUSION

The rarity of cleft lip, alveolus and/or palate in the African native documented previously may no longer be tenable as observe in this study. Management outcome has improved owing to the collaboration with SmileTrain, USA, along with multidisciplinary approach.

摘要

背景

颅面结构的发育是一个复杂的过程,众多步骤中的任何一个环节受到干扰都可能导致口面部裂隙的发生。这是一种从早期就适合手术治疗的异常情况,全球不同研究人员报告的人口统计学模式存在冲突。有几个因素对手术结果至关重要。

目的

研究唇腭裂、牙槽突裂和腭裂的人口统计学特征及治疗结果,并强调近年来有助于改善治疗的因素。

设计

描述性队列研究。

地点

三级医疗机构。

方法

对7年零10个月期间所有连续接受唇腭裂、牙槽突裂和腭裂(CLAP)治疗的患者进行研究。

结果

2001年1月1日至2008年12月31日,对149例患者进行了唇腭裂、牙槽突裂和腭裂修复手术,发病率为2.1/1000活产儿。其中,在最初的6又1/3年里,每年平均有4.5例患者接受手术,共27例;在接下来的1又1/2年里,有122例(81.9%)患者接受手术,每年平均81.6例。他们的年龄在3个月至60岁之间,男性77例(51.7%),女性72例(48.3%)。唇裂是主要表现形式的有108例(72.5%),其中72例(66.7%)为左侧唇裂。双侧唇裂14例(9.4%)。5例(约3.4%)患者伴有其他异常,其中3例(60.0%)为唇腭裂、牙槽突裂和腭裂,2例(40.0%)为单纯唇裂或腭裂。唇裂修复技术采用米勒法和诺德胡夫法,腭裂修复采用两瓣腭成形术加腭内肌成形术。142例(95..3%)手术成功,7例(4.7%)患者出现并发症。

结论

如本研究中所观察到的,先前记录的非洲本土人群中唇腭裂、牙槽突裂和/或腭裂的罕见情况可能不再成立。由于与美国微笑列车组织的合作以及多学科方法,治疗结果有所改善。

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