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唇腭裂:乔斯的经历。

Cleft lip and palate: the Jos experience.

作者信息

Orkar K S, Ugwu B T, Momoh J T

机构信息

Department of Surgery, Jos University Teaching Hospital, P.M.B. 2076, Jos, Nigeria.

出版信息

East Afr Med J. 2002 Oct;79(10):510-3. doi: 10.4314/eamj.v79i10.8811.

Abstract

OBJECTIVE

To determine the pattern of occurrence of cleft lip/palate and the factors that may have influenced treatment outcome.

DESIGN

Descriptive Study.

SETTING

Jos University Teaching Hospital, Jos, Nigeria.

SUBJECT

This study included 107 consecutive patients with cleft lip/palate managed between January 1991 and June 1997.

MAIN OUTCOME MEASURES

The pattern of occurrence of cleft lip/palate, the peculiarities of the malformation in this environment as well as factors that influenced treatment outcome.

RESULTS

The 107 patients were aged between one day and twenty-six years at presentation. There were three adults aged between 18 and 26 years with a mean of 22.3 years and 104 children with a mean age of 9.5 months. The male/female ratio was 1. 1:1, the anomaly was 2.4 times commoner on the left and the cleft lip alone was the most frequent mode of presentation (52%). The incidence was higher in the 3rd and 4th siblings. In 13% of these patients, there were other associated congenital anomalies such as Van der Woude's Syndrome, Down's Syndrome and congenital heart disease. Complications were noted in 16(14.9%) patients and these included dehiscence after repair in 8(7.5%) patients, oronasal fistulae in 2(1.9%), nasal speech in 4(3.7%) and hypertrophic scar in 2(1.9%). Eighty nine percent of these repairs were satisfactory to the parents of the affected children. All the adult patients were satisfied with their repair.

CONCLUSION

The low incidence of this anomaly in our environment may be due to underreporting in the rural areas. Public enlightenment programs should help improve early presentation.

摘要

目的

确定唇腭裂的发病模式以及可能影响治疗效果的因素。

设计

描述性研究。

地点

尼日利亚乔斯市乔斯大学教学医院。

研究对象

本研究纳入了1991年1月至1997年6月期间连续收治的107例唇腭裂患者。

主要观察指标

唇腭裂的发病模式、该环境下畸形的特点以及影响治疗效果的因素。

结果

107例患者就诊时年龄在1天至26岁之间。有3名18至26岁的成年人,平均年龄为22.3岁,104名儿童,平均年龄为9.5个月。男女比例为1.1:1,该畸形在左侧的发生率是右侧的2.4倍,单纯唇裂是最常见的表现形式(52%)。在第3和第4个兄弟姐妹中发病率较高。在这些患者中,13%伴有其他先天性异常,如范德伍迪综合征、唐氏综合征和先天性心脏病。16例(14.9%)患者出现并发症,其中8例(7.5%)为修复后裂开,2例(1.9%)为口鼻瘘,4例(3.7%)为鼻音,2例(1.9%)为肥厚性瘢痕。这些修复中有89%让患儿家长满意。所有成年患者对修复效果都很满意。

结论

我们所处环境中这种畸形的低发病率可能是由于农村地区报告不足。公众宣传项目应有助于改善早期就诊情况。

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