Pineda Roberta G, Reynolds Lauren C, Seefeldt Kristin, Hilton Claudia L, Rogers Cynthia L, Inder Terrie E
Roberta G. Pineda, PhD, OTR/L, is Assistant Professor, Program in Occupational Therapy and Department of Pediatrics, Washington University School of Medicine, St. Louis, MO;
Lauren C. Reynolds, OTD, OTR/L, is Research Coordinator, Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO.
Am J Occup Ther. 2016 Jan-Feb;70(1):7001220010p1-8. doi: 10.5014/ajot.2016.017558.
To investigate changes in head lag across postmenstrual age and define associations between head lag and (1) perinatal exposures and (2) neurodevelopment.
Sixty-four infants born ≤ 30 wk gestation had head lag assessed before and at term-equivalent age. Neurobehavior was assessed at term age. At 2 yr, neurodevelopmental testing was conducted.
Head lag decreased with advancing postmenstrual age, but 58% (n = 37) of infants continued to demonstrate head lag at term. Head lag was associated with longer stay in the neonatal intensive care unit (p = .009), inotrope use (p = .04), sepsis (p = .02), longer endotracheal intubation (p = .01), and cerebral injury (p = .006). Head lag was related to alterations in early neurobehavior (p < .03), but no associations with neurodevelopment were found at 2 yr.
Head lag was related to medical factors and early neurobehavior, but it may not be a good predictor of outcome when used in isolation.
研究月经后年龄阶段头后仰延迟的变化情况,并确定头后仰延迟与(1)围产期暴露因素以及(2)神经发育之间的关联。
对64例孕周≤30周出生的婴儿在足月前及足月矫正年龄时进行头后仰延迟评估。在足月时评估神经行为。在2岁时进行神经发育测试。
随着月经后年龄的增加,头后仰延迟现象减少,但58%(n = 37)的婴儿在足月时仍存在头后仰延迟。头后仰延迟与新生儿重症监护病房住院时间延长(p = 0.009)、使用血管活性药物(p = 0.04)、败血症(p = 0.02)、气管插管时间延长(p = 0.01)以及脑损伤(p = 0.006)相关。头后仰延迟与早期神经行为改变有关(p < 0.03),但在2岁时未发现与神经发育存在关联。
头后仰延迟与医疗因素及早期神经行为有关,但单独使用时可能并非预后的良好预测指标。